C₁₉H₁₂F₃N₃O₃

Base Information

Chemical Name:C₁₉H₁₂F₃N₃O₃
CAS No.:1334721-43-5
Molecular Formula:C₁₉H₁₂F₃N₃O₃
Molecular Weight:387.318
Hs Code.:

C<sub>19</sub>H<sub>12</sub>F<sub>3</sub>N<sub>3</sub>O<sub>3</sub>

Synonyms:C₁₉H₁₂F₃N₃O₃

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of C₁₉H₁₂F₃N₃O₃

Chemical Property:

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Technology Process of C₁₉H₁₂F₃N₃O₃

There total 5 articles about C₁₉H₁₂F₃N₃O₃ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 136918-14-4,85-41-6
phthalimide

: 1202942-30-0
{1-[4-(trifluoromethoxy)phenyl]-1H-pyrazol-3-yl}methanol

: 1334721-43-5
C₁₉H₁₂F₃N₃O₃

Guidance literature:: phthalimide; {1-[4-(trifluoromethoxy)phenyl]-1H-pyrazol-3-yl}methanol; With triphenylphosphine; diethylazodicarboxylate; In tetrahydrofuran; at 0 - 20 ℃; for 4h;

With water; In tetrahydrofuran; at 20 ℃;

Reference yield:

: 461-82-5
4-(trifluoromethoxy)aniline

: 1334721-43-5
C₁₉H₁₂F₃N₃O₃

Guidance literature:: Multi-step reaction with 5 steps

1.1: sodium nitrite; tetrafluoroboric acid / water / 0.5 h / 0 - 5 °C

2.1: pyridine / water / 0.5 h / -5 °C

3.1: triethylamine; bicyclo[2.2.1]hepta-2,5-diene / toluene / 1 h / 70 °C

4.1: lithium aluminium tetrahydride / tetrahydrofuran / 1 h / 0 - 20 °C

4.2: 0 °C

5.1: triphenylphosphine; diethylazodicarboxylate / tetrahydrofuran / 4 h / 0 - 20 °C

5.2: 20 °C

With pyridine; lithium aluminium tetrahydride; tetrafluoroboric acid; bicyclo[2.2.1]hepta-2,5-diene; triethylamine; triphenylphosphine; sodium nitrite; diethylazodicarboxylate; In tetrahydrofuran; water; toluene;

Reference yield:

: 1403941-82-1
(E)-ethyl 2-chloro-2-(2-(4-(trifluoromethoxy)phenyl)hydrazono)acetate

: 1334721-43-5
C₁₉H₁₂F₃N₃O₃

Guidance literature:: Multi-step reaction with 3 steps

1.1: triethylamine; bicyclo[2.2.1]hepta-2,5-diene / toluene / 1 h / 70 °C

2.1: lithium aluminium tetrahydride / tetrahydrofuran / 1 h / 0 - 20 °C

2.2: 0 °C

3.1: triphenylphosphine; diethylazodicarboxylate / tetrahydrofuran / 4 h / 0 - 20 °C

3.2: 20 °C

With lithium aluminium tetrahydride; bicyclo[2.2.1]hepta-2,5-diene; triethylamine; triphenylphosphine; diethylazodicarboxylate; In tetrahydrofuran; toluene;