(5aR,9aR)-3-isopropyl-1,4-diphenyl-3,5,5a,6,7,8,9,9a-octahydro-imidazo[1,2-a]quinoxaline

Base Information

• Chemical Name: (5aR,9aR)-3-isopropyl-1,4-diphenyl-3,5,5a,6,7,8,9,9a-octahydro-imidazo[1,2-a]quinoxaline
• CAS No.: 1094598-59-0
• Molecular Formula: C₂₅H₂₉N₃
• Molecular Weight: 371.525
• Mol file: 1094598-59-0.mol

Synonyms:(5aR,9aR)-3-isopropyl-1,4-diphenyl-3,5,5a,6,7,8,9,9a-octahydro-imidazo[1,2-a]quinoxaline

Chemical Property of (5aR,9aR)-3-isopropyl-1,4-diphenyl-3,5,5a,6,7,8,9,9a-octahydro-imidazo[1,2-a]quinoxaline

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (5aR,9aR)-3-isopropyl-1,4-diphenyl-3,5,5a,6,7,8,9,9a-octahydro-imidazo[1,2-a]quinoxaline

There total 1 articles about (5aR,9aR)-3-isopropyl-1,4-diphenyl-3,5,5a,6,7,8,9,9a-octahydro-imidazo[1,2-a]quinoxaline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

C6H5CHNC6H10N2C3H2(C6H5)CH(CH3)2(1+)*Br(1-)=(C6H5CHNC6H10N2C3H2(C6H5)CH(CH3)2)Br → (5aR,9aR)-3-isopropyl-1,4-diphenyl-3,5,5a,6,7,8,9,9a-octahydro-imidazo[1,2-a]quinoxaline (1094598-59-0)

Guidance literature:

With sodium hydride; In tetrahydrofuran; at 25 ℃; for 16h; Inert atmosphere;

DOI:10.1021/ol802572n

Reference yield:

(5aR,9aR)-3-isopropyl-1,4-diphenyl-3,5,5a,6,7,8,9,9a-octahydro-imidazo[1,2-a]quinoxaline (1094598-59-0) → (4S,5aR,9aR)-3-isopropyl-1,4-diphenyl-4,5,5a,6,7,8,9,9a-octahydro-imidazo[1,2-a]quinoxalin-3-ium tetrafluoroborate + (4R,5aR,9aR)-3-isopropyl-1,4-diphenyl-4,5,5a,6,7,8,9,9a-octahydro-imidazo[1,2-a]quinoxalin-3-ium tetrafluoroborate

Guidance literature:

With tetrafluoroboric acid; In diethyl ether; at -78 - 25 ℃; optical yield given as %de; Inert atmosphere;

DOI:10.1021/ol802572n