N-<4-<2-hydroxy-3-<4-(2-pyridinyl)-1-piperazinyl>propoxy>phenyl>methanesulfonamide

Base Information

Chemical Name:N-<4-<2-hydroxy-3-<4-(2-pyridinyl)-1-piperazinyl>propoxy>phenyl>methanesulfonamide
CAS No.:133863-95-3
Molecular Formula:C₁₉H₂₆N₄O₄S
Molecular Weight:406.506
Hs Code.:

Synonyms:N-<4-<2-hydroxy-3-<4-(2-pyridinyl)-1-piperazinyl>propoxy>phenyl>methanesulfonamide

Suppliers and Price of N-<4-<2-hydroxy-3-<4-(2-pyridinyl)-1-piperazinyl>propoxy>phenyl>methanesulfonamide

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of N-<4-<2-hydroxy-3-<4-(2-pyridinyl)-1-piperazinyl>propoxy>phenyl>methanesulfonamide

Chemical Property:

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Technology Process of N-<4-<2-hydroxy-3-<4-(2-pyridinyl)-1-piperazinyl>propoxy>phenyl>methanesulfonamide

There total 5 articles about N-<4-<2-hydroxy-3-<4-(2-pyridinyl)-1-piperazinyl>propoxy>phenyl>methanesulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 66.0%

: 34803-66-2
1-(2-pyridyl)piperazine

: 81783-51-9
2-[(4-(methanesulfonamido)phenoxy)methyl]oxirane

: 133863-95-3
N-<4-<2-hydroxy-3-<4-(2-pyridinyl)-1-piperazinyl>propoxy>phenyl>methanesulfonamide

Guidance literature:: In acetonitrile; Heating;
DOI:10.1021/jm00115a010

Reference yield:

: 1568-66-7
1-allyloxy-4-nitrobenzene

: 133863-95-3
N-<4-<2-hydroxy-3-<4-(2-pyridinyl)-1-piperazinyl>propoxy>phenyl>methanesulfonamide

Guidance literature:: Multi-step reaction with 4 steps

1: 81 percent / SnCl₂*2H₂O, conc. HCl / 0.33 h / 55 °C

2: 73 percent / pyridine / 72 h / Ambient temperature

3: 65 percent / 3-chloroperoxybenzoic acid / CH₂Cl₂ / 18 h / Heating

4: 66 percent / acetonitrile / Heating

With pyridine; hydrogenchloride; 3-chloro-benzenecarboperoxoic acid; tin(ll) chloride; In dichloromethane; acetonitrile;
DOI:10.1021/jm00115a010

Reference yield:

: 1688-69-3
p-allyloxyaniline

: 133863-95-3
N-<4-<2-hydroxy-3-<4-(2-pyridinyl)-1-piperazinyl>propoxy>phenyl>methanesulfonamide

Guidance literature:: Multi-step reaction with 3 steps

1: 73 percent / pyridine / 72 h / Ambient temperature

2: 65 percent / 3-chloroperoxybenzoic acid / CH₂Cl₂ / 18 h / Heating

3: 66 percent / acetonitrile / Heating

With pyridine; 3-chloro-benzenecarboperoxoic acid; In dichloromethane; acetonitrile;
DOI:10.1021/jm00115a010