ethyl 3-[4-(5-{3-chloro-4-[(1-methylethyl)oxy]phenyl}-1,2,4-oxadiazol-3-yl)-1H-pyrrolo[2,3-c]pyridin-1-yl]propanoate

Base Information

Chemical Name:ethyl 3-[4-(5-{3-chloro-4-[(1-methylethyl)oxy]phenyl}-1,2,4-oxadiazol-3-yl)-1H-pyrrolo[2,3-c]pyridin-1-yl]propanoate
CAS No.:1258875-15-8
Molecular Formula:C₂₃H₂₃ClN₄O₄
Molecular Weight:454.913
Hs Code.:

Synonyms:ethyl 3-[4-(5-{3-chloro-4-[(1-methylethyl)oxy]phenyl}-1,2,4-oxadiazol-3-yl)-1H-pyrrolo[2,3-c]pyridin-1-yl]propanoate

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of ethyl 3-[4-(5-{3-chloro-4-[(1-methylethyl)oxy]phenyl}-1,2,4-oxadiazol-3-yl)-1H-pyrrolo[2,3-c]pyridin-1-yl]propanoate

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Purity/Quality:: 98% ^*data from raw suppliers

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Technology Process of ethyl 3-[4-(5-{3-chloro-4-[(1-methylethyl)oxy]phenyl}-1,2,4-oxadiazol-3-yl)-1H-pyrrolo[2,3-c]pyridin-1-yl]propanoate

There total 1 articles about ethyl 3-[4-(5-{3-chloro-4-[(1-methylethyl)oxy]phenyl}-1,2,4-oxadiazol-3-yl)-1H-pyrrolo[2,3-c]pyridin-1-yl]propanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1258875-14-7
4-(5-{3-chloro-4-[(1-methylethyl)oxy]phenyl}-1,2,4-oxadiazol-3-yl)-1H-pyrrolo[2,3-c]pyridine

: 140-88-5,9003-32-1
ethyl acrylate

: 1258875-15-8
ethyl 3-[4-(5-{3-chloro-4-[(1-methylethyl)oxy]phenyl}-1,2,4-oxadiazol-3-yl)-1H-pyrrolo[2,3-c]pyridin-1-yl]propanoate

Guidance literature:: With 1,8-diazabicyclo[5.4.0]undec-7-ene; In acetonitrile; at 82 ℃; for 12h;

Reference yield:

: 1258875-15-8
ethyl 3-[4-(5-{3-chloro-4-[(1-methylethyl)oxy]phenyl}-1,2,4-oxadiazol-3-yl)-1H-pyrrolo[2,3-c]pyridin-1-yl]propanoate

: 1258874-92-8
3-[4-(5-{3-chloro-4-[(1-methylethyl)oxy]phenyl}-1,2,4-oxadiazol-3-yl)-1H-pyrrolo[2,3-c]pyridin-1-yl]propanoic acid

Guidance literature:: ethyl 3-[4-(5-{3-chloro-4-[(1-methylethyl)oxy]phenyl}-1,2,4-oxadiazol-3-yl)-1H-pyrrolo[2,3-c]pyridin-1-yl]propanoate; With water; sodium hydroxide; In isopropyl alcohol; at 80 ℃; for 1h;

In isopropyl alcohol; pH=6; Cooling with ice;