Technology Process of C22H28O5
There total 9 articles about C22H28O5 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
tert-butyl diethylphosphonoacetate;
With
sodium hydride;
In
tetrahydrofuran; hexane;
at 0 - 20 ℃;
for 0.583333h;
Inert atmosphere;
C16H18O4;
In
tetrahydrofuran; hexane;
at 55 ℃;
for 18h;
diastereoselective reaction;
Inert atmosphere;
DOI:10.1021/ja411270d
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: trifluoroacetic acid / chloroform / 20 °C / Inert atmosphere
2.1: 4-methylmorpholine N-oxide; tetrapropylammonium perruthennate / acetonitrile / 1 h / 0 °C / Molecular sieve; Inert atmosphere
3.1: tetrabutyl ammonium fluoride; acetic acid / dichloromethane; tetrahydrofuran / 14 h / 20 °C / Inert atmosphere
4.1: sodium hydride / tetrahydrofuran; hexane / 0.58 h / 0 - 20 °C / Inert atmosphere
4.2: 18 h / 55 °C / Inert atmosphere
With
tetrapropylammonium perruthennate; tetrabutyl ammonium fluoride; sodium hydride; acetic acid; 4-methylmorpholine N-oxide; trifluoroacetic acid;
In
tetrahydrofuran; hexane; dichloromethane; chloroform; acetonitrile;
4.1: |Horner-Wadsworth-Emmons Olefination / 4.2: |Horner-Wadsworth-Emmons Olefination;
DOI:10.1021/ja411270d
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: tetrabutyl ammonium fluoride; acetic acid / dichloromethane; tetrahydrofuran / 14 h / 20 °C / Inert atmosphere
2.1: sodium hydride / tetrahydrofuran; hexane / 0.58 h / 0 - 20 °C / Inert atmosphere
2.2: 18 h / 55 °C / Inert atmosphere
With
tetrabutyl ammonium fluoride; sodium hydride; acetic acid;
In
tetrahydrofuran; hexane; dichloromethane;
2.1: |Horner-Wadsworth-Emmons Olefination / 2.2: |Horner-Wadsworth-Emmons Olefination;
DOI:10.1021/ja411270d
