(2S,2'R)-2-fluoromethyl-2-<<(4-methylphenyl)thio>methyl>oxirane

Base Information

Chemical Name:(2S,2'R)-2-fluoromethyl-2-<<(4-methylphenyl)thio>methyl>oxirane
CAS No.:158560-45-3
Molecular Formula:C₁₇H₁₇FOS
Molecular Weight:288.386
Hs Code.:

(2S,2'R)-2-fluoromethyl-2-<<(4-methylphenyl)thio><phenyl>methyl>oxirane

Synonyms:(2S,2'R)-2-fluoromethyl-2-<<(4-methylphenyl)thio>methyl>oxirane

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Chemical Property of (2S,2'R)-2-fluoromethyl-2-<<(4-methylphenyl)thio>methyl>oxirane

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Technology Process of (2S,2'R)-2-fluoromethyl-2-<<(4-methylphenyl)thio>methyl>oxirane

There total 3 articles about (2S,2'R)-2-fluoromethyl-2-<<(4-methylphenyl)thio>methyl>oxirane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 158560-34-0
(2S,2'R,R_S)-2-fluoromethyl-2-<<(4-methylphenyl)sulfinyl>methyl>oxirane

: 158560-45-3
(2S,2'R)-2-fluoromethyl-2-<<(4-methylphenyl)thio>methyl>oxirane

Guidance literature:: With trifluoroacetic anhydride; sodium iodide; In acetone; at -40 ℃;

Reference yield:

: 115879-08-8
(3R,R_S)-1-fluoro-3-<(4-methylphenyl)sulfinyl>-3-phenylpropan-2-one

: 158560-45-3
(2S,2'R)-2-fluoromethyl-2-<<(4-methylphenyl)thio>methyl>oxirane

Guidance literature:: Multi-step reaction with 2 steps

1: 83.8 percent / methanol; diethyl ether / 0 °C

2: 98 percent / sodium iodide, trifluoroacetic anhydride / acetone / -40 °C

With trifluoroacetic anhydride; sodium iodide; In methanol; diethyl ether; acetone;

Reference yield:

: (3R)/(3S)-1-fluoro-3-<(4-methylphenyl)sulfinyl>-3-phenylpropan-2-one

: 158560-45-3
(2S,2'R)-2-fluoromethyl-2-<<(4-methylphenyl)thio>methyl>oxirane

Guidance literature:: Multi-step reaction with 2 steps

1: 70 percent / tetrahydrofuran; diethyl ether / 0 °C

2: 98 percent / sodium iodide, trifluoroacetic anhydride / acetone / -40 °C

With trifluoroacetic anhydride; sodium iodide; In tetrahydrofuran; diethyl ether; acetone;