(2R,4S,5R,6S)-5,6-Bis-benzyloxy-4-(tert-butyl-dimethyl-silanyloxy)-2-methyl-dihydro-pyran-3-one O-[(2S,3R,6R)-4-(tert-butyl-dimethyl-silanyloxy)-3-hydroxy-6-methyl-3,6-dihydro-2H-pyran-2-yl]-oxime

Base Information

Chemical Name:(2R,4S,5R,6S)-5,6-Bis-benzyloxy-4-(tert-butyl-dimethyl-silanyloxy)-2-methyl-dihydro-pyran-3-one O-[(2S,3R,6R)-4-(tert-butyl-dimethyl-silanyloxy)-3-hydroxy-6-methyl-3,6-dihydro-2H-pyran-2-yl]-oxime
CAS No.:126900-90-1
Molecular Formula:C₃₈H₅₉NO₈Si₂
Molecular Weight:714.059
Hs Code.:

(2R,4S,5R,6S)-5,6-Bis-benzyloxy-4-(tert-butyl-dimethyl-silanyloxy)-2-methyl-dihydro-pyran-3-one O-[(2S,3R,6R)-4-(tert-butyl-dimethyl-silanyloxy)-3-hydroxy-6-methyl-3,6-dihydro-2H-pyran-2-yl]-oxime

Synonyms:(2R,4S,5R,6S)-5,6-Bis-benzyloxy-4-(tert-butyl-dimethyl-silanyloxy)-2-methyl-dihydro-pyran-3-one O-[(2S,3R,6R)-4-(tert-butyl-dimethyl-silanyloxy)-3-hydroxy-6-methyl-3,6-dihydro-2H-pyran-2-yl]-oxime

Suppliers and Price of (2R,4S,5R,6S)-5,6-Bis-benzyloxy-4-(tert-butyl-dimethyl-silanyloxy)-2-methyl-dihydro-pyran-3-one O-[(2S,3R,6R)-4-(tert-butyl-dimethyl-silanyloxy)-3-hydroxy-6-methyl-3,6-dihydro-2H-pyran-2-yl]-oxime

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (2R,4S,5R,6S)-5,6-Bis-benzyloxy-4-(tert-butyl-dimethyl-silanyloxy)-2-methyl-dihydro-pyran-3-one O-[(2S,3R,6R)-4-(tert-butyl-dimethyl-silanyloxy)-3-hydroxy-6-methyl-3,6-dihydro-2H-pyran-2-yl]-oxime

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (2R,4S,5R,6S)-5,6-Bis-benzyloxy-4-(tert-butyl-dimethyl-silanyloxy)-2-methyl-dihydro-pyran-3-one O-[(2S,3R,6R)-4-(tert-butyl-dimethyl-silanyloxy)-3-hydroxy-6-methyl-3,6-dihydro-2H-pyran-2-yl]-oxime

There total 10 articles about (2R,4S,5R,6S)-5,6-Bis-benzyloxy-4-(tert-butyl-dimethyl-silanyloxy)-2-methyl-dihydro-pyran-3-one O-[(2S,3R,6R)-4-(tert-butyl-dimethyl-silanyloxy)-3-hydroxy-6-methyl-3,6-dihydro-2H-pyran-2-yl]-oxime which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: 126900-89-8
3-Chloro-benzoic acid (2S,3R,6R)-2-[(2R,4S,5R,6S)-5,6-bis-benzyloxy-4-(tert-butyl-dimethyl-silanyloxy)-2-methyl-dihydro-pyran-(3Z)-ylideneaminooxy]-4-(tert-butyl-dimethyl-silanyloxy)-6-methyl-3,6-dihydro-2H-pyran-3-yl ester

: 126900-90-1
(2R,4S,5R,6S)-5,6-Bis-benzyloxy-4-(tert-butyl-dimethyl-silanyloxy)-2-methyl-dihydro-pyran-3-one O-[(2S,3R,6R)-4-(tert-butyl-dimethyl-silanyloxy)-3-hydroxy-6-methyl-3,6-dihydro-2H-pyran-2-yl]-oxime

Guidance literature:: With diisobutylaluminium hydride; In dichloromethane; at -78 ℃; for 1h;

Reference yield:

: 127000-08-2
Benzoic acid (2R,3R,4R)-4-hydroxy-2-methyl-3,4-dihydro-2H-pyran-3-yl ester

: 126900-90-1
(2R,4S,5R,6S)-5,6-Bis-benzyloxy-4-(tert-butyl-dimethyl-silanyloxy)-2-methyl-dihydro-pyran-3-one O-[(2S,3R,6R)-4-(tert-butyl-dimethyl-silanyloxy)-3-hydroxy-6-methyl-3,6-dihydro-2H-pyran-2-yl]-oxime

Guidance literature:: Multi-step reaction with 9 steps

1: 55 percent / 55percent m-chloroperoxybenzoic acid, MgSO₄ / CH₂Cl₂ / 0.5 h / 0 °C

2: 67 percent / imidazole / CH₂Cl₂ / 30 h / 25 °C

3: 1.) (COCl)2, DMSO, 2.) Et₃N / 1.) CH₂Cl₂, -78 deg C to 25 deg C

4: Zn(BH₄)2, NH₄Cl / diethyl ether / 0.33 h / 0 °C

5: diisopropyl azodicarboxylate, Ph₃P / tetrahydrofuran / 0.5 h / 25 °C

6: N₂H₄ / methanol / 0.17 h / 25 °C

7: pyridinium p-toluenesulfonate (PPTS) / benzene / 3 h / 25 °C

8: 99 percent / 2,6-lutidine / 0.5 h / -25 - 0 °C

9: 91 percent / DIBAL / CH₂Cl₂ / 1 h / -78 °C

With 1H-imidazole; 2,6-dimethylpyridine; zinc(II) tetrahydroborate; oxalyl dichloride; di-isopropyl azodicarboxylate; pyridinium p-toluenesulfonate; diisobutylaluminium hydride; magnesium sulfate; ammonium chloride; dimethyl sulfoxide; triethylamine; 3-chloro-benzenecarboperoxoic acid; triphenylphosphine; hydrazine; In tetrahydrofuran; methanol; diethyl ether; dichloromethane; benzene;

Reference yield:

: 126900-82-1
Benzoic acid (2R,3S,4R)-4-acetoxy-2-methyl-3,4-dihydro-2H-pyran-3-yl ester

: 126900-90-1
(2R,4S,5R,6S)-5,6-Bis-benzyloxy-4-(tert-butyl-dimethyl-silanyloxy)-2-methyl-dihydro-pyran-3-one O-[(2S,3R,6R)-4-(tert-butyl-dimethyl-silanyloxy)-3-hydroxy-6-methyl-3,6-dihydro-2H-pyran-2-yl]-oxime

Guidance literature:: Multi-step reaction with 10 steps

1: 72 percent / DIBAL / CH₂Cl₂ / 2.5 h / -78 °C

2: 55 percent / 55percent m-chloroperoxybenzoic acid, MgSO₄ / CH₂Cl₂ / 0.5 h / 0 °C

3: 67 percent / imidazole / CH₂Cl₂ / 30 h / 25 °C

4: 1.) (COCl)2, DMSO, 2.) Et₃N / 1.) CH₂Cl₂, -78 deg C to 25 deg C

5: Zn(BH₄)2, NH₄Cl / diethyl ether / 0.33 h / 0 °C

6: diisopropyl azodicarboxylate, Ph₃P / tetrahydrofuran / 0.5 h / 25 °C

7: N₂H₄ / methanol / 0.17 h / 25 °C

8: pyridinium p-toluenesulfonate (PPTS) / benzene / 3 h / 25 °C

9: 99 percent / 2,6-lutidine / 0.5 h / -25 - 0 °C

10: 91 percent / DIBAL / CH₂Cl₂ / 1 h / -78 °C

With 1H-imidazole; 2,6-dimethylpyridine; zinc(II) tetrahydroborate; oxalyl dichloride; di-isopropyl azodicarboxylate; pyridinium p-toluenesulfonate; diisobutylaluminium hydride; magnesium sulfate; ammonium chloride; dimethyl sulfoxide; triethylamine; 3-chloro-benzenecarboperoxoic acid; triphenylphosphine; hydrazine; In tetrahydrofuran; methanol; diethyl ether; dichloromethane; benzene;