Technology Process of 2-deuterio ethyl benzoate
There total 4 articles about 2-deuterio ethyl benzoate which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
Cyclohexanethiol; 10-phenyl-10H-phenothiazine; dideuterioformic acid; N-ethyl-N,N-diisopropylamine;
In
acetonitrile;
at 20 ℃;
for 0.0833333h;
under 2250.23 Torr;
Reagent/catalyst;
Irradiation;
Sealed tube;
Inert atmosphere;
DOI:10.1002/ejoc.201900952
- Guidance literature:
-
With
deuterium;
bis(triphenylphosphine)(1,5-cyclooctadiene)iridium(I) BF4;
In
dichloromethane;
Title compound not separated from byproducts;
DOI:10.1016/S0040-4039(01)01266-7
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 10-phenyl-10H-phenothiazine; Cyclohexanethiol; formic acid; N-ethyl-N,N-diisopropylamine / acetonitrile / 0.02 h / 20 °C / Irradiation; Flow reactor
2: 10-phenyl-10H-phenothiazine; Cyclohexanethiol; N-ethyl-N,N-diisopropylamine; dideuterioformic acid / acetonitrile / 0.08 h / 20 °C / 2250.23 Torr / Irradiation; Sealed tube; Inert atmosphere
With
formic acid; Cyclohexanethiol; 10-phenyl-10H-phenothiazine; dideuterioformic acid; N-ethyl-N,N-diisopropylamine;
In
acetonitrile;
DOI:10.1002/ejoc.201900952
