N,N'-bis[4-(methoxymethoxy)benzoyl]-2,6-bis[(6-aminopyrid-2-yl)ethynyl]-4-n-butoxypyridine

Base Information

Chemical Name:N,N'-bis[4-(methoxymethoxy)benzoyl]-2,6-bis[(6-aminopyrid-2-yl)ethynyl]-4-n-butoxypyridine
CAS No.:251640-61-6
Molecular Formula:C₄₁H₃₇N₅O₇
Molecular Weight:711.774
Hs Code.:

Synonyms:N,N'-bis[4-(methoxymethoxy)benzoyl]-2,6-bis[(6-aminopyrid-2-yl)ethynyl]-4-n-butoxypyridine

Suppliers and Price of N,N'-bis[4-(methoxymethoxy)benzoyl]-2,6-bis[(6-aminopyrid-2-yl)ethynyl]-4-n-butoxypyridine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of N,N'-bis[4-(methoxymethoxy)benzoyl]-2,6-bis[(6-aminopyrid-2-yl)ethynyl]-4-n-butoxypyridine

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of N,N'-bis[4-(methoxymethoxy)benzoyl]-2,6-bis[(6-aminopyrid-2-yl)ethynyl]-4-n-butoxypyridine

There total 7 articles about N,N'-bis[4-(methoxymethoxy)benzoyl]-2,6-bis[(6-aminopyrid-2-yl)ethynyl]-4-n-butoxypyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 50.0%

: 173314-96-0
4-n-butoxy-2,6-dibromopyridine

: 251640-59-2
N-(6-ethynyl-2-pyridyl)-4-(methoxymethoxy)benzamide

: 251640-61-6
N,N'-bis[4-(methoxymethoxy)benzoyl]-2,6-bis[(6-aminopyrid-2-yl)ethynyl]-4-n-butoxypyridine

Guidance literature:: With triethylamine; bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; at 60 ℃;
DOI:10.1021/jo9911138

Reference yield:

: 94-26-8
4-hydroxybenzoic acid, butyl ester

: 251640-61-6
N,N'-bis[4-(methoxymethoxy)benzoyl]-2,6-bis[(6-aminopyrid-2-yl)ethynyl]-4-n-butoxypyridine

Guidance literature:: Multi-step reaction with 6 steps

1: 92 percent / NaH / tetrahydrofuran / 12 h / 20 °C

2: 87 percent / KOH / ethanol / 3 h / 20 °C

3: 52 percent / Ph₃P; BrCCl₃ / tetrahydrofuran / 1.5 h / Heating

4: 96 percent / Et₂NH / (Ph₃P)2PdCl₂; CuI / 4 h / 20 °C

5: 73 percent / NaH / toluene / 0.67 h / 120 °C

6: 50 percent / Et₃N / (Ph₃P)2PdCl₂; CuI / 60 °C

With potassium hydroxide; Bromotrichloromethane; sodium hydride; diethylamine; triethylamine; triphenylphosphine; bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; In tetrahydrofuran; ethanol; toluene; 1: Etherification / 2: Hydrolysis / 3: Acylation / 4: Sonogashira reaction / 5: Elimination / 6: Sonogashira reaction;
DOI:10.1021/jo9911138

Reference yield:

: 19798-81-3,1184170-10-2
2-Amino-6-bromopyridine

: 251640-61-6
N,N'-bis[4-(methoxymethoxy)benzoyl]-2,6-bis[(6-aminopyrid-2-yl)ethynyl]-4-n-butoxypyridine

Guidance literature:: Multi-step reaction with 4 steps

1: 52 percent / Ph₃P; BrCCl₃ / tetrahydrofuran / 1.5 h / Heating

2: 96 percent / Et₂NH / (Ph₃P)2PdCl₂; CuI / 4 h / 20 °C

3: 73 percent / NaH / toluene / 0.67 h / 120 °C

4: 50 percent / Et₃N / (Ph₃P)2PdCl₂; CuI / 60 °C

With Bromotrichloromethane; sodium hydride; diethylamine; triethylamine; triphenylphosphine; bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; In tetrahydrofuran; toluene; 1: Acylation / 2: Sonogashira reaction / 3: Elimination / 4: Sonogashira reaction;
DOI:10.1021/jo9911138