[2-(4-chloro-phenyl)-5,6-difluoro-benzoimidazol-1-yl]-cyclohexyl-acetaldehyde

Base Information

Chemical Name:[2-(4-chloro-phenyl)-5,6-difluoro-benzoimidazol-1-yl]-cyclohexyl-acetaldehyde
CAS No.:1265884-95-4
Molecular Formula:C₂₁H₁₉ClF₂N₂O
Molecular Weight:388.844
Hs Code.:

Synonyms:[2-(4-chloro-phenyl)-5,6-difluoro-benzoimidazol-1-yl]-cyclohexyl-acetaldehyde

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of [2-(4-chloro-phenyl)-5,6-difluoro-benzoimidazol-1-yl]-cyclohexyl-acetaldehyde

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Technology Process of [2-(4-chloro-phenyl)-5,6-difluoro-benzoimidazol-1-yl]-cyclohexyl-acetaldehyde

There total 1 articles about [2-(4-chloro-phenyl)-5,6-difluoro-benzoimidazol-1-yl]-cyclohexyl-acetaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.0%

: 1289117-59-4
2-[2-(4-chloro-phenyl)-5,6-difluoro-benzoimidazol-1-yl]-2-cyclohexyl-ethanol

: 1265884-95-4
[2-(4-chloro-phenyl)-5,6-difluoro-benzoimidazol-1-yl]-cyclohexyl-acetaldehyde

Guidance literature:: With Dess-Martin periodane; In dichloromethane; at 20 ℃; for 2h;

Reference yield: 67.0%

: 1265884-95-4
[2-(4-chloro-phenyl)-5,6-difluoro-benzoimidazol-1-yl]-cyclohexyl-acetaldehyde

: 873-74-5
4-Aminobenzonitrile

: 1265884-96-5
4-{2-[2-(4-chloro-phenyl)-5,6-difluoro-benzoimidazol-1-yl]-2-cyclohexyl-ethylamino}-benzonitrile

Guidance literature:: With phenylsilane; at 100 ℃; for 0.35h; Microwave irradiation;

Reference yield:

: 1265884-95-4
[2-(4-chloro-phenyl)-5,6-difluoro-benzoimidazol-1-yl]-cyclohexyl-acetaldehyde

: 1253-46-9
4-methoxycarbonylbenzyltriphenylphosphonium bromide

: 1265884-91-0
4-{3-[2-(4-chloro-phenyl)-5,6-difluoro-benzoimidazol-1-yl]-3-cyclohexyl-propenyl}-benzoic acid methyl ester

Guidance literature:: 4-methoxycarbonylbenzyltriphenylphosphonium bromide; With potassium tert-butylate; In tetrahydrofuran; for 0.25h; Cooling with ice;

[2-(4-chloro-phenyl)-5,6-difluoro-benzoimidazol-1-yl]-cyclohexyl-acetaldehyde; In tetrahydrofuran; at 0 - 20 ℃;