exo-6,exo-7-isopropylidenedioxy-3-(2-methylphenyl)-8-oxabicyclo[3.2.1]octan-endo-3-ol

Base Information

Chemical Name:exo-6,exo-7-isopropylidenedioxy-3-(2-methylphenyl)-8-oxabicyclo[3.2.1]octan-endo-3-ol
CAS No.:262421-31-8
Molecular Formula:C₁₇H₂₂O₄
Molecular Weight:290.359
Hs Code.:

Synonyms:exo-6,exo-7-isopropylidenedioxy-3-(2-methylphenyl)-8-oxabicyclo[3.2.1]octan-endo-3-ol

Suppliers and Price of exo-6,exo-7-isopropylidenedioxy-3-(2-methylphenyl)-8-oxabicyclo[3.2.1]octan-endo-3-ol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of exo-6,exo-7-isopropylidenedioxy-3-(2-methylphenyl)-8-oxabicyclo[3.2.1]octan-endo-3-ol

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of exo-6,exo-7-isopropylidenedioxy-3-(2-methylphenyl)-8-oxabicyclo[3.2.1]octan-endo-3-ol

There total 3 articles about exo-6,exo-7-isopropylidenedioxy-3-(2-methylphenyl)-8-oxabicyclo[3.2.1]octan-endo-3-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 46.0%

: 66149-68-6
exo-6,exo-7-isopropylidenedioxy-8-oxabicyclo[3.2.1]octan-3-one

: 95-46-5
2-methylphenyl bromide

: 262421-31-8
exo-6,exo-7-isopropylidenedioxy-3-(2-methylphenyl)-8-oxabicyclo[3.2.1]octan-endo-3-ol

Guidance literature:: 2-methylphenyl bromide; With iodine; magnesium; In diethyl ether; for 1h;

exo-6,exo-7-isopropylidenedioxy-8-oxabicyclo[3.2.1]octan-3-one; In tetrahydrofuran; diethyl ether; at 20 ℃; for 12h;
DOI:10.1071/CH99044

Reference yield:

: 40458-77-3
8-oxabicyclo[3.2.1]oct-6-en-3-one

: 262421-31-8
exo-6,exo-7-isopropylidenedioxy-3-(2-methylphenyl)-8-oxabicyclo[3.2.1]octan-endo-3-ol

Guidance literature:: Multi-step reaction with 3 steps

1.1: OsO₄; 30 percent H₂O₂ / acetone; diethyl ether; 2-methyl-propan-2-ol / 38 h / 20 °C

2.1: TsOH; CuSO₄ / 96 h / 20 °C

3.1: Mg; I₂ / diethyl ether / 1 h

3.2: 46 percent / diethyl ether; tetrahydrofuran / 12 h / 20 °C

With osmium(VIII) oxide; dihydrogen peroxide; iodine; toluene-4-sulfonic acid; copper(II) sulfate; magnesium; In diethyl ether; acetone; tert-butyl alcohol; 1.1: Oxidation / 2.1: cyclocondensation / 3.1: Metallation / 3.2: Grignard reaction;
DOI:10.1071/CH99044

Reference yield:

: 94369-41-2
(1S,5R,6S,7R)-6,7-Dihydroxy-8-oxa-bicyclo[3.2.1]octan-3-one

: 262421-31-8
exo-6,exo-7-isopropylidenedioxy-3-(2-methylphenyl)-8-oxabicyclo[3.2.1]octan-endo-3-ol

Guidance literature:: Multi-step reaction with 2 steps

1.1: TsOH; CuSO₄ / 96 h / 20 °C

2.1: Mg; I₂ / diethyl ether / 1 h

2.2: 46 percent / diethyl ether; tetrahydrofuran / 12 h / 20 °C

With iodine; toluene-4-sulfonic acid; copper(II) sulfate; magnesium; In diethyl ether; 1.1: cyclocondensation / 2.1: Metallation / 2.2: Grignard reaction;
DOI:10.1071/CH99044