N-[5-amino-2-(3(R)-amino-1-piperidinyl)phenyl]-1H-imidazoie-2-carboxamide

Base Information

Chemical Name:N-[5-amino-2-(3(R)-amino-1-piperidinyl)phenyl]-1H-imidazoie-2-carboxamide
CAS No.:1350916-71-0
Molecular Formula:C₁₅H₂₀N₆O
Molecular Weight:300.363
Hs Code.:

Synonyms:N-[5-amino-2-(3(R)-amino-1-piperidinyl)phenyl]-1H-imidazoie-2-carboxamide

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Chemical Property of N-[5-amino-2-(3(R)-amino-1-piperidinyl)phenyl]-1H-imidazoie-2-carboxamide

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Technology Process of N-[5-amino-2-(3(R)-amino-1-piperidinyl)phenyl]-1H-imidazoie-2-carboxamide

There total 2 articles about N-[5-amino-2-(3(R)-amino-1-piperidinyl)phenyl]-1H-imidazoie-2-carboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

: 1350918-04-5
C₂₅H₃₆N₆O₅

: 1350916-71-0
N-[5-amino-2-(3(R)-amino-1-piperidinyl)phenyl]-1H-imidazoie-2-carboxamide

Guidance literature:: C₂₅H₃₆N₆O₅; With trifluoroacetic acid; at 20 ℃; for 2h;

With ammonia; In methanol; dichloromethane;

Reference yield:

: 1350918-02-3
C₂₁H₃₄N₄O₄

: 1350916-71-0
N-[5-amino-2-(3(R)-amino-1-piperidinyl)phenyl]-1H-imidazoie-2-carboxamide

Guidance literature:: Multi-step reaction with 2 steps

1: N-ethyl-N,N-diisopropylamine; HATU / N,N-dimethyl-formamide / 20 °C

2: trifluoroacetic acid / 2 h / 20 °C

With N-ethyl-N,N-diisopropylamine; HATU; trifluoroacetic acid; In N,N-dimethyl-formamide;