(S)-methyl 2-(4-(phenyl(3-(trifluoromethyl)phenyl)-methyl)piperazin-1-yl)-acetate

Base Information

Chemical Name:(S)-methyl 2-(4-(phenyl(3-(trifluoromethyl)phenyl)-methyl)piperazin-1-yl)-acetate
CAS No.:1000691-88-2
Molecular Formula:C₂₁H₂₃F₃N₂O₂
Molecular Weight:392.421
Hs Code.:

Synonyms:(S)-methyl 2-(4-(phenyl(3-(trifluoromethyl)phenyl)-methyl)piperazin-1-yl)-acetate

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Chemical Property of (S)-methyl 2-(4-(phenyl(3-(trifluoromethyl)phenyl)-methyl)piperazin-1-yl)-acetate

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Technology Process of (S)-methyl 2-(4-(phenyl(3-(trifluoromethyl)phenyl)-methyl)piperazin-1-yl)-acetate

There total 1 articles about (S)-methyl 2-(4-(phenyl(3-(trifluoromethyl)phenyl)-methyl)piperazin-1-yl)-acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 48.0%

: 519139-53-8
1-(phenyl(3-(trifluoromethyl)phenyl)methyl)piperazine

: 96-32-2
bromoacetic acid methyl ester

: 1000691-88-2
(S)-methyl 2-(4-(phenyl(3-(trifluoromethyl)phenyl)-methyl)piperazin-1-yl)-acetate

Guidance literature:: With triethylamine; In acetonitrile; at 20 ℃; for 18.5h;

Reference yield: 84.0%

: 1000691-88-2
(S)-methyl 2-(4-(phenyl(3-(trifluoromethyl)phenyl)-methyl)piperazin-1-yl)-acetate

: 2-(4-(phenyl(3-(trifluoromethyl)phenyl)methyl)piperazin-1-yl)acetic acid

Guidance literature:: (S)-methyl 2-(4-(phenyl(3-(trifluoromethyl)phenyl)-methyl)piperazin-1-yl)-acetate; With methanol; sodium hydroxide; water; at 70 ℃; for 1h;

With hydrogenchloride; water; pH=4; Product distribution / selectivity;