C₇₀H₁₂₁O₁₅Si₂N

Base Information

• Chemical Name: C₇₀H₁₂₁O₁₅Si₂N
• CAS No.: 930803-47-7
• Molecular Formula: C₇₀H₁₂₁NO₁₅Si₂
• Molecular Weight: 1272.9
• Mol file: 930803-47-7.mol

Synonyms:C₇₀H₁₂₁O₁₅Si₂N

Chemical Property of C₇₀H₁₂₁O₁₅Si₂N

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₇₀H₁₂₁O₁₅Si₂N

There total 47 articles about C₇₀H₁₂₁O₁₅Si₂N which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

C66H117O13Si2N (930803-46-6) + Allyl chloroformate (2937-50-0) → C70H121O15Si2N (930803-47-7)

Guidance literature:

With 4-pyrrolidin-1-ylpyridine; In dichloromethane;

DOI:10.1002/anie.200604053

Reference yield:

C10H15S2O2Br (930803-25-1) → C70H121O15Si2N (930803-47-7)

Guidance literature:

Multi-step reaction with 14 steps

1.1: 99 percent / diisobutylaluminum hydride / CH₂Cl₂ / -45 °C

2.1: 70 percent / methanesulfonyl chloride; triethylamine; 4-(dimethylamino)pyridine / lithium bromide / CH₂Cl₂; dimethylformamide

3.1: 99 percent / LiBHEt₃ / tetrahydrofuran / 0 °C

4.1: tert-butyllithium / tetrahydrofuran / -96 - -78 °C

5.1: 99 percent / 2,6-lutidine / CH₂Cl₂ / 0.67 h / -78 °C

6.1: 77 percent / tert-butyllithium; hexamethylphosphoramide / tetrahydrofuran / -78 - -40 °C

7.1: 84 percent / (bis(trifluoroacetoxy)iodo)benzene / tetrahydrofuran; H₂O; methanol / 20 °C

8.1: 84 percent / 1,3-dicyclohexylcarbodiimide; 4-(dimethylamino)pyridine / CH₂Cl₂ / 24 h / -5 °C

9.1: 93 percent / 2,3-dichloro-5,6-dicyano-1,4-benzoquinone / CH₂Cl₂ / 20 °C / pH 7

10.1: 99 percent / (COCl)2; dimethyl sulfoxide; triethylamine / CH₂Cl₂

11.1: 82 percent / CrCl₂ / tetrahydrofuran / 0 - 20 °C

12.1: N-methylpyrrolidinone; [Pd{P(2-furyl)3}2Cl₂]; hexamethyltin / 20 °C

12.2: [Pd{P(2-furyl)3}2Cl₂]; N-methylpyrrolidinone / 20 °C

13.1: 81 percent / LiAlH(OtBu)3 / tetrahydrofuran / -10 °C

14.1: 81 percent / 4-pyrrolidinopyridine / CH₂Cl₂

With 2,6-dimethylpyridine; 1-methyl-pyrrolidin-2-one; chromium dichloride; N,N,N,N,N,N-hexamethylphosphoric triamide; dmap; oxalyl dichloride; tert.-butyl lithium; hexamethyldistannane; diisobutylaluminium hydride; lithium triethylborohydride; 4-pyrrolidin-1-ylpyridine; dimethyl sulfoxide; methanesulfonyl chloride; lithium tri-t-butoxyaluminum hydride; triethylamine; dicyclohexyl-carbodiimide; 2,3-dicyano-5,6-dichloro-p-benzoquinone; bis-[(trifluoroacetoxy)iodo]benzene; lithium bromide; In tetrahydrofuran; methanol; dichloromethane; water; N,N-dimethyl-formamide; 10.1: Swern oxidation;

DOI:10.1002/anie.200604053

Reference yield:

C9H15S2OBr (930803-26-2) → C70H121O15Si2N (930803-47-7)

Guidance literature:

Multi-step reaction with 13 steps

1.1: 70 percent / methanesulfonyl chloride; triethylamine; 4-(dimethylamino)pyridine / lithium bromide / CH₂Cl₂; dimethylformamide

2.1: 99 percent / LiBHEt₃ / tetrahydrofuran / 0 °C

3.1: tert-butyllithium / tetrahydrofuran / -96 - -78 °C

4.1: 99 percent / 2,6-lutidine / CH₂Cl₂ / 0.67 h / -78 °C

5.1: 77 percent / tert-butyllithium; hexamethylphosphoramide / tetrahydrofuran / -78 - -40 °C

6.1: 84 percent / (bis(trifluoroacetoxy)iodo)benzene / tetrahydrofuran; H₂O; methanol / 20 °C

7.1: 84 percent / 1,3-dicyclohexylcarbodiimide; 4-(dimethylamino)pyridine / CH₂Cl₂ / 24 h / -5 °C

8.1: 93 percent / 2,3-dichloro-5,6-dicyano-1,4-benzoquinone / CH₂Cl₂ / 20 °C / pH 7

9.1: 99 percent / (COCl)2; dimethyl sulfoxide; triethylamine / CH₂Cl₂

10.1: 82 percent / CrCl₂ / tetrahydrofuran / 0 - 20 °C

11.1: N-methylpyrrolidinone; [Pd{P(2-furyl)3}2Cl₂]; hexamethyltin / 20 °C

11.2: [Pd{P(2-furyl)3}2Cl₂]; N-methylpyrrolidinone / 20 °C

12.1: 81 percent / LiAlH(OtBu)3 / tetrahydrofuran / -10 °C

13.1: 81 percent / 4-pyrrolidinopyridine / CH₂Cl₂

With 2,6-dimethylpyridine; 1-methyl-pyrrolidin-2-one; chromium dichloride; N,N,N,N,N,N-hexamethylphosphoric triamide; dmap; oxalyl dichloride; tert.-butyl lithium; hexamethyldistannane; lithium triethylborohydride; 4-pyrrolidin-1-ylpyridine; dimethyl sulfoxide; methanesulfonyl chloride; lithium tri-t-butoxyaluminum hydride; triethylamine; dicyclohexyl-carbodiimide; 2,3-dicyano-5,6-dichloro-p-benzoquinone; bis-[(trifluoroacetoxy)iodo]benzene; lithium bromide; In tetrahydrofuran; methanol; dichloromethane; water; N,N-dimethyl-formamide; 9.1: Swern oxidation;

DOI:10.1002/anie.200604053

upstream raw materials:

C₆₆H₁₁₇O₁₃Si₂N

Allyl chloroformate

(2R,4S)-5-(4-methoxybenzyloxy)-2,4-dimethylpentanal

C₉H₁₄S₂Br₂

Downstream raw materials:

C₇₀H₁₂₃O₁₆Si₂N

C₇₆H₁₃₇O₁₆Si₃N

C₇₃H₁₃₀O₁₅Si₃NBr

C₇₉H₁₃₄O₁₆Si₃NBr