[4-Amino-2-(4-hydroxy-phenyl)-1H-imidazo[4,5-c]pyridin-6-yl]-carbamic acid ethyl ester; hydrochloride

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Chemical Name:[4-Amino-2-(4-hydroxy-phenyl)-1H-imidazo[4,5-c]pyridin-6-yl]-carbamic acid ethyl ester; hydrochloride
CAS No.:109182-66-3
Molecular Formula:C₁₅H₁₅N₅O₃*2ClH
Molecular Weight:386.238
Hs Code.:

Synonyms:[4-Amino-2-(4-hydroxy-phenyl)-1H-imidazo[4,5-c]pyridin-6-yl]-carbamic acid ethyl ester; hydrochloride

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Chemical Property of [4-Amino-2-(4-hydroxy-phenyl)-1H-imidazo[4,5-c]pyridin-6-yl]-carbamic acid ethyl ester; hydrochloride

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Technology Process of [4-Amino-2-(4-hydroxy-phenyl)-1H-imidazo[4,5-c]pyridin-6-yl]-carbamic acid ethyl ester; hydrochloride

There total 3 articles about [4-Amino-2-(4-hydroxy-phenyl)-1H-imidazo[4,5-c]pyridin-6-yl]-carbamic acid ethyl ester; hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

: 109182-56-1
[4-(Benzhydryl-amino)-2-(4-hydroxy-phenyl)-1H-imidazo[4,5-c]pyridin-6-yl]-carbamic acid ethyl ester

: 109182-66-3
[4-Amino-2-(4-hydroxy-phenyl)-1H-imidazo[4,5-c]pyridin-6-yl]-carbamic acid ethyl ester; hydrochloride

Guidance literature:: With hydrogenchloride; at 25 ℃; for 165h;
DOI:10.1021/jm00393a011

Reference yield:

: 38359-80-7
ethyl <4,5-diamino-6-<(diphenylmethyl)amino>pyridin-2-yl>carbamate dihydrochloride

: 109182-66-3
[4-Amino-2-(4-hydroxy-phenyl)-1H-imidazo[4,5-c]pyridin-6-yl]-carbamic acid ethyl ester; hydrochloride

Guidance literature:: Multi-step reaction with 2 steps

1: 50 percent / AcONa / methanol / 3.5 h / Heating

2: 82 percent / conc. HCl / 165 h / 25 °C

With hydrogenchloride; sodium acetate; In methanol;
DOI:10.1021/jm00393a011

Reference yield:

: 123-08-0,65581-83-1
4-hydroxy-benzaldehyde

: 109182-66-3
[4-Amino-2-(4-hydroxy-phenyl)-1H-imidazo[4,5-c]pyridin-6-yl]-carbamic acid ethyl ester; hydrochloride

Guidance literature:: Multi-step reaction with 2 steps

1: 50 percent / AcONa / methanol / 3.5 h / Heating

2: 82 percent / conc. HCl / 165 h / 25 °C

With hydrogenchloride; sodium acetate; In methanol;
DOI:10.1021/jm00393a011