3-AMINO-5-PHENYL-1H-PYRAZOLE-4-CARBONITRILE

Base Information

• Chemical Name: 3-AMINO-5-PHENYL-1H-PYRAZOLE-4-CARBONITRILE
• CAS No.: 42754-61-0
• Molecular Formula: C10H8 N4
• Molecular Weight: 184.2
• Hs Code.: 2933199090
• Mol file: 42754-61-0.mol

Synonyms:Pyrazole-4-carbonitrile,3(or 5)-amino-5(or 3)-phenyl- (6CI); 3-Amino-4-cyano-5-phenylpyrazole;3-Amino-5-phenyl-1H-pyrazole-4-carbonitrile

Chemical Property of 3-AMINO-5-PHENYL-1H-PYRAZOLE-4-CARBONITRILE

Chemical Property:

• PSA: 78.49000
• LogP: 2.11178

Purity/Quality:

98%min ^*data from raw suppliers

3-AMINO-5-PHENYL-1H-PYRAZOLE-4-CARBONITRILE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-AMINO-5-PHENYL-1H-PYRAZOLE-4-CARBONITRILE

There total 29 articles about 3-AMINO-5-PHENYL-1H-PYRAZOLE-4-CARBONITRILE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

3-chloro-5-phenyl-1,2-thiazole-4-carbonitrile (28989-23-3) → 3-amino-5-phenyl-1H-pyrazole-4-carbonitrile (42754-61-0,957046-71-8)

Guidance literature:

With hydrazine hydrate; at 80 ℃; for 1h;

DOI:10.1039/b607442a

Reference yield: 100.0%

3-bromo-5-phenylisothiazole-4-carbonitrile (647016-68-0) → 3-amino-5-phenyl-1H-pyrazole-4-carbonitrile (42754-61-0,957046-71-8)

Guidance literature:

With hydrazine; at 20 ℃; for 0.166667h;

DOI:10.1016/j.tet.2009.06.041

Reference yield: 99.0%

3-(N-benzylamino)-5-phenyl-1H-pyrazole-4-carbonitrile (1187733-93-2) → 3-amino-5-phenyl-1H-pyrazole-4-carbonitrile (42754-61-0,957046-71-8)

Guidance literature:

With water; In methanol; at 20 ℃; for 0.25h;

DOI:10.1016/j.tet.2009.06.041

upstream raw materials:

2-(methoxyphenylmethylene)malononitrile

2-benzoylmalononitrile

3-chloro-5-phenyl-1,2-thiazole-4-carbonitrile

3-methoxy-5-phenylisothiazole-4-carbonitrile

Downstream raw materials:

3-nitro-7-phenyl-8-cyanopyrazolo<1,5-a>pyrimidine

2-phenyl-5-(2-thienyl)pyrazolo[1,5-a]pyrimidine-3,6-dicarbonitrile

C₁₈H₉N₅S

2-phenyl-7-(2-thienyl)pyrazolo[1,5-a]pyrimidine-3-carbonitrile