C₁₉H₁₅F₂N₉O₂

Base Information

• Chemical Name: C₁₉H₁₅F₂N₉O₂
• CAS No.: 1112968-62-3
• Molecular Formula: C₁₉H₁₅F₂N₉O₂
• Molecular Weight: 439.384
• Mol file: 1112968-62-3.mol

Synonyms:C₁₉H₁₅F₂N₉O₂

Chemical Property of C₁₉H₁₅F₂N₉O₂

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₁₉H₁₅F₂N₉O₂

There total 6 articles about C₁₉H₁₅F₂N₉O₂ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C2HF3O2*C17H15F2N7O2 + N′-(2,2-dichloroethylidene)-4-methylbenzenesulfonohydrazide (56020-01-0) → C19H15F2N9O2 (1112968-62-3)

Guidance literature:

With N-ethyl-N,N-diisopropylamine; In methanol; at 0 ℃; for 3h;

Reference yield:

C14H10BrF2NO2 (1112969-24-0) → C19H15F2N9O2 (1112968-62-3)

Guidance literature:

Multi-step reaction with 4 steps

1: lithium tert-butoxide / tetrahydrofuran; N,N-dimethyl-formamide / 0 - 20 °C

2: potassium acetate / dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH₂Cl₂ / N,N-dimethyl-formamide / 80 °C

3: 1,2-dichloro-ethane / 2 h / 0 - 20 °C

4: N-ethyl-N,N-diisopropylamine / methanol / 3 h / 0 °C

With potassium acetate; N-ethyl-N,N-diisopropylamine; lithium tert-butoxide; dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH₂Cl₂; In tetrahydrofuran; methanol; 1,2-dichloro-ethane; N,N-dimethyl-formamide;

Reference yield:

C15H17BrF2N2O4 (1112969-25-1) → C19H15F2N9O2 (1112968-62-3)

Guidance literature:

Multi-step reaction with 3 steps

1: potassium acetate / dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH₂Cl₂ / N,N-dimethyl-formamide / 80 °C

2: 1,2-dichloro-ethane / 2 h / 0 - 20 °C

3: N-ethyl-N,N-diisopropylamine / methanol / 3 h / 0 °C

With potassium acetate; N-ethyl-N,N-diisopropylamine; dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH₂Cl₂; In methanol; 1,2-dichloro-ethane; N,N-dimethyl-formamide;

upstream raw materials:

N′-(2,2-dichloroethylidene)-4-methylbenzenesulfonohydrazide

2-(2-methyl-2H-tetrazol-5-yl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine

C₁₄H₁₀BrF₂NO₂

C₁₅H₁₇BrF₂N₂O₄

Refernces

• 1、 -. "Antimicrobial ortho-Fluorophenyl Oxazolidinones For Treatment of Bacterial Infections". Page/Page column 30. . Retrieved 2009/03/07.