2,5-Piperazinedione,1-acetyl-6-methyl-3-methylene-,(6S)-(9CI)

Base Information

Chemical Name:2,5-Piperazinedione,1-acetyl-6-methyl-3-methylene-,(6S)-(9CI)
CAS No.:342416-72-2
Molecular Formula:C₈H₁₀N₂O₃
Molecular Weight:182.179
Hs Code.:2933599090
Mol file:342416-72-2.mol

Synonyms:2,5-Piperazinedione,1-acetyl-6-methyl-3-methylene-,(6S)-(9CI);(6S)-1-(ACETYLOXY)-6-METHYL-3-METHYLIDENEPIPERAZINE-2,5-DIONE

Suppliers and Price of 2,5-Piperazinedione,1-acetyl-6-methyl-3-methylene-,(6S)-(9CI)

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of 2,5-Piperazinedione,1-acetyl-6-methyl-3-methylene-,(6S)-(9CI)

Chemical Property:

Boiling Point:456.9±45.0 °C(Predicted)
PKA:10.18±0.40(Predicted)
PSA：69.97000
Density:1.26±0.1 g/cm3(Predicted)
LogP:-0.39270

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 2,5-Piperazinedione,1-acetyl-6-methyl-3-methylene-,(6S)-(9CI)

There total 1 articles about 2,5-Piperazinedione,1-acetyl-6-methyl-3-methylene-,(6S)-(9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

: 108-24-7
acetic anhydride

: 342416-68-6
(S)-3-Hydroxymethyl-6-methyl-piperazine-2,5-dione

: 342416-72-2
(S)-1-Acetyl-6-methyl-3-methylene-piperazine-2,5-dione

Guidance literature:: With dmap; triethylamine;
DOI:10.1016/S0040-4039(01)00151-4

Reference yield:

: 342416-72-2
(S)-1-Acetyl-6-methyl-3-methylene-piperazine-2,5-dione

: 8-methyl-3-(2,4,6-trimethylphenyl)-1-oxa-2,6,9-triazaspiro[4.5]dec-2-ene-7,10-dione

Guidance literature:: Multi-step reaction with 2 steps

1: CH₂Cl₂ / 168 h / 20 °C

2: hydrazine hydrate / dimethylformamide / 16 h / 20 °C

With hydrazine hydrate; In dichloromethane; N,N-dimethyl-formamide;
DOI:10.1016/j.tet.2003.09.040