Toluene-4-sulfonic acid 2-(3,4-dimethoxy-phenyl)-3,5,8-trimethoxy-4-oxo-4H-chromen-7-yl ester

Base Information

• Chemical Name: Toluene-4-sulfonic acid 2-(3,4-dimethoxy-phenyl)-3,5,8-trimethoxy-4-oxo-4H-chromen-7-yl ester
• CAS No.: 117155-46-1
• Molecular Formula: C₂₇H₂₆O₁₀S
• Molecular Weight: 542.563
• Mol file: 117155-46-1.mol

Synonyms:Toluene-4-sulfonic acid 2-(3,4-dimethoxy-phenyl)-3,5,8-trimethoxy-4-oxo-4H-chromen-7-yl ester

Chemical Property of Toluene-4-sulfonic acid 2-(3,4-dimethoxy-phenyl)-3,5,8-trimethoxy-4-oxo-4H-chromen-7-yl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

Useful:

Technology Process of Toluene-4-sulfonic acid 2-(3,4-dimethoxy-phenyl)-3,5,8-trimethoxy-4-oxo-4H-chromen-7-yl ester

There total 1 articles about Toluene-4-sulfonic acid 2-(3,4-dimethoxy-phenyl)-3,5,8-trimethoxy-4-oxo-4H-chromen-7-yl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

7-hydroxy-3,3',4',5,8-pentamethoxyflavone (33554-63-1) + p-toluenesulfonyl chloride (98-59-9) → Toluene-4-sulfonic acid 2-(3,4-dimethoxy-phenyl)-3,5,8-trimethoxy-4-oxo-4H-chromen-7-yl ester (117155-46-1)

Guidance literature:

With potassium carbonate; In acetone; Heating;

DOI:10.1246/bcsj.61.441

Reference yield:

Toluene-4-sulfonic acid 2-(3,4-dimethoxy-phenyl)-3,5,8-trimethoxy-4-oxo-4H-chromen-7-yl ester (117155-46-1) → Toluene-4-sulfonic acid 2-(3,4-dimethoxy-phenyl)-5-hydroxy-3,8-dimethoxy-4-oxo-4H-chromen-7-yl ester + Toluene-4-sulfonic acid 2-(3,4-dimethoxy-phenyl)-3-hydroxy-5,8-dimethoxy-4-oxo-4H-chromen-7-yl ester

Guidance literature:

With hydrogenchloride; aluminum tri-bromide; In acetonitrile; Title compound not separated from byproducts; 1.) rt., 2 h; 2.) 70-80 deg C, 15-30 min;

DOI:10.1246/bcsj.61.441

Reference yield:

Toluene-4-sulfonic acid 2-(3,4-dimethoxy-phenyl)-3,5,8-trimethoxy-4-oxo-4H-chromen-7-yl ester (117155-46-1) → Acetic acid 3,7-diacetoxy-2-(3,4-dimethoxy-phenyl)-8-methoxy-4-oxo-4H-chromen-5-yl ester

Guidance literature:

Multi-step reaction with 2 steps

2: pyridine / 24 h / Ambient temperature

With pyridine;

DOI:10.1246/bcsj.61.441

upstream raw materials:

7-hydroxy-3,3',4',5,8-pentamethoxyflavone

p-toluenesulfonyl chloride

Downstream raw materials:

2-(3,4-Dimethoxy-phenyl)-3,5,7-trihydroxy-8-methoxy-chromen-4-one