N-oxide of 9-benzyl-6-nitro-γ-carboline

Base Information

• Chemical Name: N-oxide of 9-benzyl-6-nitro-γ-carboline
• CAS No.: 144781-20-4
• Molecular Formula: C₁₈H₁₃N₃O₃
• Molecular Weight: 319.32
• Mol file: 144781-20-4.mol

Synonyms:N-oxide of 9-benzyl-6-nitro-γ-carboline

Chemical Property of N-oxide of 9-benzyl-6-nitro-γ-carboline

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

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Technology Process of N-oxide of 9-benzyl-6-nitro-γ-carboline

There total 1 articles about N-oxide of 9-benzyl-6-nitro-γ-carboline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

6-nitro-9-benzyl-γ-carboline (133415-05-1) → N-oxide of 9-benzyl-6-nitro-γ-carboline (144781-20-4)

Guidance literature:

With dihydrogen peroxide; In acetic acid; at 95 ℃; for 8h;

DOI:10.1007/BF00767002

Reference yield: 84.0%

N-oxide of 9-benzyl-6-nitro-γ-carboline (144781-20-4) → 6-nitro-9-benzyl-1,2-dehydro-γ-carboline-4-one (144781-22-6)

Guidance literature:

With acetic anhydride; for 10h; Heating;

DOI:10.1007/BF00767002

Reference yield:

N-oxide of 9-benzyl-6-nitro-γ-carboline (144781-20-4) → 4-benzylamino-6-nitro-9-benzyl-γ-carboline

Guidance literature:

Multi-step reaction with 3 steps

1: 84 percent / acetic anhydride / 10 h / Heating

2: 75 percent / POCl₃, Et₃N*HCl / dioxane / 5 h / Heating

3: 78 percent / 11 h / 130 - 140 °C

With acetic anhydride; triethylamine hydrochloride; trichlorophosphate; In 1,4-dioxane;

DOI:10.1007/BF00767002

upstream raw materials:

6-nitro-9-benzyl-γ-carboline

Downstream raw materials:

6-nitro-9-benzyl-1,2-dehydro-γ-carboline-4-one

4-chloro-6-nitro-9-benzyl-γ-carboline