(2R)-2-(N-tert-Butoxycarbonyl-N-methylamino)-3-(2-naphthyl)propionic acid methylester

Base Information

Chemical Name:(2R)-2-(N-tert-Butoxycarbonyl-N-methylamino)-3-(2-naphthyl)propionic acid methylester
CAS No.:182492-96-2
Molecular Formula:C₂₀H₂₅NO₄
Molecular Weight:343.423
Hs Code.:

Synonyms:(2R)-2-(N-tert-Butoxycarbonyl-N-methylamino)-3-(2-naphthyl)propionic acid methylester

Suppliers and Price of (2R)-2-(N-tert-Butoxycarbonyl-N-methylamino)-3-(2-naphthyl)propionic acid methylester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (2R)-2-(N-tert-Butoxycarbonyl-N-methylamino)-3-(2-naphthyl)propionic acid methylester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (2R)-2-(N-tert-Butoxycarbonyl-N-methylamino)-3-(2-naphthyl)propionic acid methylester

There total 1 articles about (2R)-2-(N-tert-Butoxycarbonyl-N-methylamino)-3-(2-naphthyl)propionic acid methylester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 42492-57-9
methyl 2-((tert-butoxycarbonyl)(methyl)amino)acetate

: 939-26-4
2-bromomethylnaphthyl bromide

: 182492-96-2
(2R)-2-(N-tert-Butoxycarbonyl-N-methylamino)-3-(2-naphthyl)propionic acid methylester

Guidance literature:: With lithium diisopropyl amide; In tetrahydrofuran; at -78 - 20 ℃;
DOI:10.1016/S0960-894X(01)00631-X

Reference yield:

: 182492-96-2
(2R)-2-(N-tert-Butoxycarbonyl-N-methylamino)-3-(2-naphthyl)propionic acid methylester

: N-methyl-N-[1-naphthalen-2-ylmethyl-3-(2-oxo-azepan-3-ylcarbamoyl)-allyl]-3,5-bis-trifluoromethyl-benzamide

Guidance literature:: Multi-step reaction with 5 steps

1.1: DIBAH / toluene / -78 °C

2.1: n-BuLi

2.2: citric acid

3.1: EDC; DMAP / CH₂Cl₂

4.1: TFA / CH₂Cl₂

5.1: Et₃N / CH₂Cl₂

With dmap; n-butyllithium; diisobutylaluminium hydride; N-(3-dimethylaminopropyl)-N-ethylcarbodiimide; triethylamine; trifluoroacetic acid; In dichloromethane; toluene;
DOI:10.1016/S0960-894X(01)00631-X

Reference yield:

: 182492-96-2
(2R)-2-(N-tert-Butoxycarbonyl-N-methylamino)-3-(2-naphthyl)propionic acid methylester

: (4R)-[N'-methyl-N'-(3,5-bistrifluoromethyl-benzoyl)-amino]-5-(naphth-2-yl)-pent-2-enoic acid N-[(R)-epsilon-caprolactam-3-yl]-amide

Guidance literature:: Multi-step reaction with 5 steps

1.1: DIBAH / toluene / -78 °C

2.1: n-BuLi

2.2: citric acid

3.1: EDC; DMAP / CH₂Cl₂

4.1: TFA / CH₂Cl₂

5.1: Et₃N / CH₂Cl₂

With dmap; n-butyllithium; diisobutylaluminium hydride; N-(3-dimethylaminopropyl)-N-ethylcarbodiimide; triethylamine; trifluoroacetic acid; In dichloromethane; toluene;
DOI:10.1016/S0960-894X(01)00631-X