N-(3,4-dimethyl-5-isoxazolyl)-2'-(formylmethyl)-N-[(2-methoxyethoxy)methyl]-4'-(2-oxazolyl)-[1,1'-biphenyl]-2-sulfonamide

Base Information

• Chemical Name: N-(3,4-dimethyl-5-isoxazolyl)-2'-(formylmethyl)-N-[(2-methoxyethoxy)methyl]-4'-(2-oxazolyl)-[1,1'-biphenyl]-2-sulfonamide
• CAS No.: 195447-13-3
• Molecular Formula: C₂₆H₂₇N₃O₇S
• Molecular Weight: 525.582
• Mol file: 195447-13-3.mol

Synonyms:N-(3,4-dimethyl-5-isoxazolyl)-2'-(formylmethyl)-N-[(2-methoxyethoxy)methyl]-4'-(2-oxazolyl)-[1,1'-biphenyl]-2-sulfonamide

Chemical Property of N-(3,4-dimethyl-5-isoxazolyl)-2'-(formylmethyl)-N-[(2-methoxyethoxy)methyl]-4'-(2-oxazolyl)-[1,1'-biphenyl]-2-sulfonamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-(3,4-dimethyl-5-isoxazolyl)-2'-(formylmethyl)-N-[(2-methoxyethoxy)methyl]-4'-(2-oxazolyl)-[1,1'-biphenyl]-2-sulfonamide

There total 2 articles about N-(3,4-dimethyl-5-isoxazolyl)-2'-(formylmethyl)-N-[(2-methoxyethoxy)methyl]-4'-(2-oxazolyl)-[1,1'-biphenyl]-2-sulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 63.0%

4'-oxazol-2-yl-2'-vinyl-biphenyl-2-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-(2-methoxy-ethoxymethyl)-amide → N-(3,4-dimethyl-5-isoxazolyl)-2'-(formylmethyl)-N-[(2-methoxyethoxy)methyl]-4'-(2-oxazolyl)-[1,1'-biphenyl]-2-sulfonamide (195447-13-3)

Guidance literature:

With toluene-4-sulfonic acid; In 1,4-dioxane; water; for 4h; Heating;

DOI:10.1021/jm020289q

Reference yield:

→ N-(3,4-dimethyl-5-isoxazolyl)-2'-(formylmethyl)-N-[(2-methoxyethoxy)methyl]-4'-(2-oxazolyl)-[1,1'-biphenyl]-2-sulfonamide (195447-13-3)

Guidance literature:

Reference yield:

N-(3,4-dimethyl-5-isoxazolyl)-2'-(formylmethyl)-N-[(2-methoxyethoxy)methyl]-4'-(2-oxazolyl)-[1,1'-biphenyl]-2-sulfonamide (195447-13-3) → 2'-[[(3,4-Dimethyl-5-isoxazolyl)[(2-methoxyethoxy)methyl]amino]sulfonyl]-4-(2-oxazolyl)[1,1'-biphenyl]-2-acetic acid (195447-14-4)

Guidance literature:

With sodium chlorite; aminosulfonic acid; In tetrahydrofuran; at 0 ℃; for 0.0333333h;

DOI:10.1021/jm020289q

Downstream raw materials:

2'-[[(3,4-Dimethyl-5-isoxazolyl)[(2-methoxyethoxy)methyl]amino]sulfonyl]-4-(2-oxazolyl)[1,1'-biphenyl]-2-acetic acid

2-{2'-[(3,4-dimethyl-isoxazol-5-yl)-(2-methoxy-ethoxymethyl)-sulfamoyl]-4-oxazol-2-yl-biphenyl-2-yl}-N,N-dimethyl-acetamide

N-(1,1-Dimethylethyl)-2'-[[(3,4-dimethyl-5-isoxazolyl)[(2-methoxyethoxy)methyl]amino]sulfonyl]-4-(2-oxazolyl)[1,1'-biphenyl]-2-acetamide