Technology Process of C17H19N2O4Cl
There total 9 articles about C17H19N2O4Cl which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
thionyl chloride;
at 78 - 80 ℃;
for 14h;
DOI:10.1021/ol071007p
- Guidance literature:
-
Multi-step reaction with 6 steps
1: 1.82 g / manganese(IV) oxide / CH2Cl2 / 20 °C
2: 90 percent / N-iodosuccinimide / tetrahydrofuran / 24 h / Heating
3: 70 percent / CuI; diisopropylamine / PdCl2(PPh3)2 / tetrahydrofuran / 20 h / 50 °C
4: 75 percent / hydrogen / Pd/C / ethyl acetate; methanol / 20 °C / atmospheric pressure
5: NaClO2; NaH2PO4*2H2O; 2-methyl-2-butene / 2-methyl-propan-2-ol; tetrahydrofuran; H2O / 1 h / 20 °C
6: 86 percent / thionyl chloride / 14 h / 78 - 80 °C
With
manganese(IV) oxide; sodium chlorite; sodium dihydrogenphosphate; N-iodo-succinimide; copper(l) iodide; thionyl chloride; 2-methyl-but-2-ene; hydrogen; diisopropylamine;
bis-triphenylphosphine-palladium(II) chloride; palladium on activated charcoal;
In
tetrahydrofuran; methanol; dichloromethane; water; ethyl acetate; tert-butyl alcohol;
3: Sonogashira coupling;
DOI:10.1021/ol071007p
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 70 percent / CuI; diisopropylamine / PdCl2(PPh3)2 / tetrahydrofuran / 20 h / 50 °C
2: 75 percent / hydrogen / Pd/C / ethyl acetate; methanol / 20 °C / atmospheric pressure
3: NaClO2; NaH2PO4*2H2O; 2-methyl-2-butene / 2-methyl-propan-2-ol; tetrahydrofuran; H2O / 1 h / 20 °C
4: 86 percent / thionyl chloride / 14 h / 78 - 80 °C
With
sodium chlorite; sodium dihydrogenphosphate; copper(l) iodide; thionyl chloride; 2-methyl-but-2-ene; hydrogen; diisopropylamine;
bis-triphenylphosphine-palladium(II) chloride; palladium on activated charcoal;
In
tetrahydrofuran; methanol; water; ethyl acetate; tert-butyl alcohol;
1: Sonogashira coupling;
DOI:10.1021/ol071007p