tert-butyl (3S,4S,5S)-3--4,5-(isopropylidenedioxy)hexanoate

Base Information

Chemical Name:tert-butyl (3S,4S,5S)-3--4,5-(isopropylidenedioxy)hexanoate
CAS No.:111554-02-0
Molecular Formula:C₃₂H₄₉NO₅Si
Molecular Weight:555.83
Hs Code.:

tert-butyl (3S,4S,5S)-3-<N-(tert-butyldimethylsiloxy)benzhydrylamino>-4,5-(isopropylidenedioxy)hexanoate

Synonyms:tert-butyl (3S,4S,5S)-3--4,5-(isopropylidenedioxy)hexanoate

Suppliers and Price of tert-butyl (3S,4S,5S)-3--4,5-(isopropylidenedioxy)hexanoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of tert-butyl (3S,4S,5S)-3--4,5-(isopropylidenedioxy)hexanoate

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of tert-butyl (3S,4S,5S)-3--4,5-(isopropylidenedioxy)hexanoate

There total 8 articles about tert-butyl (3S,4S,5S)-3--4,5-(isopropylidenedioxy)hexanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 74786-02-0
1-(tert-butyldimethylsilyloxy)-1-tert-butoxyethylene

: 111524-16-4
N-<<(4S,5S)-2,2,5-trimethyl-1,3-dioxolan-4-yl>methylene>benzhydrylamine N-oxide

: 111554-02-0
tert-butyl (3S,4S,5S)-3--4,5-(isopropylidenedioxy)hexanoate

Guidance literature:: zinc(II) iodide; In dichloromethane; acetonitrile; at -78 ℃;
DOI:10.1016/S0040-4039(00)95946-X

Reference yield:

: 84519-53-9
(4R,5S)-2,2,5-trimethyl-1,3-dioxolane-4-carbaldehyde

: 111554-02-0
tert-butyl (3S,4S,5S)-3--4,5-(isopropylidenedioxy)hexanoate

Guidance literature:: Multi-step reaction with 2 steps

1: 64 percent / sodium sulfate / CH₂Cl₂ / 15 h / Ambient temperature

2: 85 percent / zinc iodide / acetonitrile; CH₂Cl₂ / 10 h / -78 °C

With sodium sulfate; zinc(II) iodide; In dichloromethane; acetonitrile;
DOI:10.1248/cpb.37.1446

Reference yield:

: 85099-89-4,109715-57-3,124019-21-2,93451-86-6
(S,S)-2,2-dimethyl-4-benzyloxymethyl-5-methyl-1,3-dioxolane

: 111554-02-0
tert-butyl (3S,4S,5S)-3--4,5-(isopropylidenedioxy)hexanoate

Guidance literature:: Multi-step reaction with 4 steps

1: 89 percent / hydrogen / 10percent palladium on carbon / ethyl acetate; acetic acid / 24 h / Ambient temperature

2: 1.) oxalyl chloride, 2.) triethylamine / 1.) DMSO, methylene chloride, 20 min, -78 deg C, 2.) DMSO, CH₂Cl₂, -78 deg C, 20 min, warm to room temperature

3: 64 percent / sodium sulfate / CH₂Cl₂ / 15 h / Ambient temperature

4: 85 percent / zinc iodide / acetonitrile; CH₂Cl₂ / 10 h / -78 °C

With oxalyl dichloride; hydrogen; sodium sulfate; triethylamine; palladium on activated charcoal; zinc(II) iodide; In dichloromethane; acetic acid; ethyl acetate; acetonitrile;
DOI:10.1248/cpb.37.1446