2-{[3-tert-butyl-1(2-methylphenyl)-1H-pyrazol-5yl]amino}-5-methoxybenzoic acid

Base Information

Chemical Name:2-{[3-tert-butyl-1(2-methylphenyl)-1H-pyrazol-5yl]amino}-5-methoxybenzoic acid
CAS No.:705275-20-3
Molecular Formula:C₂₂H₂₅N₃O₃
Molecular Weight:379.459
Hs Code.:

Synonyms:2-{[3-tert-butyl-1(2-methylphenyl)-1H-pyrazol-5yl]amino}-5-methoxybenzoic acid

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Chemical Property of 2-{[3-tert-butyl-1(2-methylphenyl)-1H-pyrazol-5yl]amino}-5-methoxybenzoic acid

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Technology Process of 2-{[3-tert-butyl-1(2-methylphenyl)-1H-pyrazol-5yl]amino}-5-methoxybenzoic acid

There total 1 articles about 2-{[3-tert-butyl-1(2-methylphenyl)-1H-pyrazol-5yl]amino}-5-methoxybenzoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 33.0%

: 22921-68-2
2-bromo-5-methoxy-benzoic acid

: 337533-96-7
5-tert-butyl-2-o-tolyl-2H-pyrazol-3-yl-amine

: 705275-20-3
2-{[3-tert-butyl-1(2-methylphenyl)-1H-pyrazol-5yl]amino}-5-methoxybenzoic acid

Guidance literature:: 2-bromo-5-methoxy-benzoic acid; 5-tert-butyl-2-o-tolyl-2H-pyrazol-3-yl-amine; With potassium carbonate; copper diacetate; In DMF (N,N-dimethyl-formamide); at 150 ℃; for 18h;

With acetic acid; In DMF (N,N-dimethyl-formamide); at 20 ℃; pH=4;

Reference yield: 49.0%

: 705275-20-3
2-{[3-tert-butyl-1(2-methylphenyl)-1H-pyrazol-5yl]amino}-5-methoxybenzoic acid

: 2-{[3-tert-butyl-1-(2-methylphenyl)-1H-pyrazol-5-yl]amino}-5-methoxybenzamide

Guidance literature:: With ammonium chloride; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; In DMF (N,N-dimethyl-formamide); for 16h;