2-(4-Phenylpiperazine)-4-phthalimidobutyric acid N-(4-fluorobenzylamide)

Base Information

Chemical Name:2-(4-Phenylpiperazine)-4-phthalimidobutyric acid N-(4-fluorobenzylamide)
CAS No.:172883-63-5
Molecular Formula:C₂₉H₂₉FN₄O₃
Molecular Weight:500.573
Hs Code.:

Synonyms:2-(4-Phenylpiperazine)-4-phthalimidobutyric acid N-(4-fluorobenzylamide)

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Chemical Property of 2-(4-Phenylpiperazine)-4-phthalimidobutyric acid N-(4-fluorobenzylamide)

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Technology Process of 2-(4-Phenylpiperazine)-4-phthalimidobutyric acid N-(4-fluorobenzylamide)

There total 3 articles about 2-(4-Phenylpiperazine)-4-phthalimidobutyric acid N-(4-fluorobenzylamide) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

: 140-75-0
para-fluorobenzylamine

: 172883-57-7
2-(4-Phenylpiperazine)-4-phthalimidobutyric acid

: 172883-63-5
2-(4-Phenylpiperazine)-4-phthalimidobutyric acid N-(4-fluorobenzylamide)

Guidance literature:: With 4-methyl-morpholine; (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; In N,N-dimethyl-formamide; for 24h; Ambient temperature;

Reference yield:

: 1074-82-4
potassium phtalimide

: 172883-63-5
2-(4-Phenylpiperazine)-4-phthalimidobutyric acid N-(4-fluorobenzylamide)

Guidance literature:: Multi-step reaction with 2 steps

1: 85 percent / various solvent(s) / 8 h / Heating

2: 89 percent / BOP, NMM / dimethylformamide / 24 h / Ambient temperature

With 4-methyl-morpholine; (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; In N,N-dimethyl-formamide;

Reference yield:

: 169894-59-1
3-(4-phenylpiperazin-1-yl)-tetrahydrofuran-2-one

: 172883-63-5
2-(4-Phenylpiperazine)-4-phthalimidobutyric acid N-(4-fluorobenzylamide)

Guidance literature:: Multi-step reaction with 2 steps

1: 85 percent / various solvent(s) / 8 h / Heating

2: 89 percent / BOP, NMM / dimethylformamide / 24 h / Ambient temperature

With 4-methyl-morpholine; (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; In N,N-dimethyl-formamide;