1-benzoyl-1,2,3,4,5,6-hexahydro-4-phenyl<1,3,6>triazocino<1,2-a>benzimidazole

Base Information

• Chemical Name: 1-benzoyl-1,2,3,4,5,6-hexahydro-4-phenyl<1,3,6>triazocino<1,2-a>benzimidazole
• CAS No.: 125605-13-2
• Molecular Formula: C₂₄H₂₂N₄O
• Molecular Weight: 382.465
• Mol file: 125605-13-2.mol

Synonyms:1-benzoyl-1,2,3,4,5,6-hexahydro-4-phenyl<1,3,6>triazocino<1,2-a>benzimidazole

Chemical Property of 1-benzoyl-1,2,3,4,5,6-hexahydro-4-phenyl<1,3,6>triazocino<1,2-a>benzimidazole

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-benzoyl-1,2,3,4,5,6-hexahydro-4-phenyl<1,3,6>triazocino<1,2-a>benzimidazole

There total 2 articles about 1-benzoyl-1,2,3,4,5,6-hexahydro-4-phenyl<1,3,6>triazocino<1,2-a>benzimidazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 22.0%

N-(1H-benzo[d]imidazol-2-yl)benzamide (7412-05-7) + aniline mustard (553-27-5) → 1-benzoyl-1,2,3,4,5,6-hexahydro-4-phenyl<1,3,6>triazocino<1,2-a>benzimidazole (125605-13-2)

Guidance literature:

With potassium tert-butylate; In N,N-dimethyl-formamide; toluene; for 6h; Heating;

DOI:10.1021/jm00082a011

Reference yield:

N,N-bis(chloroethyl)aniline + N-(1H-benzo[d]imidazol-2-yl)benzamide (7412-05-7) → 1-benzoyl-1,2,3,4,5,6-hexahydro-4-phenyl<1,3,6>triazocino<1,2-a>benzimidazole (125605-13-2)

Guidance literature:

In N,N-dimethyl-formamide; toluene;

Reference yield: 76.0%

1-benzoyl-1,2,3,4,5,6-hexahydro-4-phenyl<1,3,6>triazocino<1,2-a>benzimidazole (125605-13-2) → 1,2,3,4,5,6-hexahydro-4-phenyl<1,3,6>triazocino<1,2-a>benzimidazole (125605-29-0)

Guidance literature:

With ammonia; In methanol; at 100 ℃; for 96h;

DOI:10.1021/jm00082a011

upstream raw materials:

N-(1H-benzo[d]imidazol-2-yl)benzamide

aniline mustard

Downstream raw materials:

1,2,3,4,5,6-hexahydro-4-phenyl<1,3,6>triazocino<1,2-a>benzimidazole

N-[4-(5,6,9,10-Tetrahydro-8H-4b,7,10,11-tetraaza-cycloocta[a]indene-7-sulfonyl)-phenyl]-methanesulfonamide