11-((6R,7S,8R,9S,13S,14S,17S)-6-Benzenesulfonyl-17-hydroxy-3-methoxy-13-methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthren-7-yl)-undecanoic acid butyl-methyl-amide

Base Information

• Chemical Name: 11-((6R,7S,8R,9S,13S,14S,17S)-6-Benzenesulfonyl-17-hydroxy-3-methoxy-13-methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthren-7-yl)-undecanoic acid butyl-methyl-amide
• CAS No.: 153004-18-3
• Molecular Formula: C₄₁H₆₁NO₅S
• Molecular Weight: 680.005

Synonyms:11-((6R,7S,8R,9S,13S,14S,17S)-6-Benzenesulfonyl-17-hydroxy-3-methoxy-13-methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthren-7-yl)-undecanoic acid butyl-methyl-amide

Chemical Property of 11-((6R,7S,8R,9S,13S,14S,17S)-6-Benzenesulfonyl-17-hydroxy-3-methoxy-13-methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthren-7-yl)-undecanoic acid butyl-methyl-amide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 11-((6R,7S,8R,9S,13S,14S,17S)-6-Benzenesulfonyl-17-hydroxy-3-methoxy-13-methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthren-7-yl)-undecanoic acid butyl-methyl-amide

There total 8 articles about 11-((6R,7S,8R,9S,13S,14S,17S)-6-Benzenesulfonyl-17-hydroxy-3-methoxy-13-methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthren-7-yl)-undecanoic acid butyl-methyl-amide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

11-((6R,7R,8R,9S,13S,14S,17S)-6-Benzenesulfonyl-17-hydroxy-3-methoxy-13-methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthren-7-yl)-undec-10-ynoic acid butyl-methyl-amide (153004-17-2) → 11-((6R,7S,8R,9S,13S,14S,17S)-6-Benzenesulfonyl-17-hydroxy-3-methoxy-13-methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthren-7-yl)-undecanoic acid butyl-methyl-amide (153004-18-3)

Guidance literature:

With hydrogen; palladium on activated charcoal; In ethyl acetate; at 22 ℃;

DOI:10.1016/0040-4039(94)88321-1

Reference yield:

N-n-butyl-N-methylamine (110-68-9) → 11-((6R,7S,8R,9S,13S,14S,17S)-6-Benzenesulfonyl-17-hydroxy-3-methoxy-13-methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthren-7-yl)-undecanoic acid butyl-methyl-amide (153004-18-3)

Guidance literature:

Multi-step reaction with 3 steps

2: 1.) methyllithium; 2.) methanolic potassium hydroxide / 1.) THF, -10 deg C to 0 deg C, 1 h

3: 80 percent / H₂ / Pd/C / ethyl acetate / 22 °C

With potassium hydroxide; methyllithium; hydrogen; palladium on activated charcoal; In ethyl acetate;

DOI:10.1016/0040-4039(94)88321-1

Reference yield:

undec-10-ynoic acid (2777-65-3) → 11-((6R,7S,8R,9S,13S,14S,17S)-6-Benzenesulfonyl-17-hydroxy-3-methoxy-13-methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthren-7-yl)-undecanoic acid butyl-methyl-amide (153004-18-3)

Guidance literature:

Multi-step reaction with 3 steps

2: 1.) methyllithium; 2.) methanolic potassium hydroxide / 1.) THF, -10 deg C to 0 deg C, 1 h

3: 80 percent / H₂ / Pd/C / ethyl acetate / 22 °C

With potassium hydroxide; methyllithium; hydrogen; palladium on activated charcoal; In ethyl acetate;

DOI:10.1016/0040-4039(94)88321-1

upstream raw materials:

11-((6R,7R,8R,9S,13S,14S,17S)-6-Benzenesulfonyl-17-hydroxy-3-methoxy-13-methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthren-7-yl)-undec-10-ynoic acid butyl-methyl-amide

N-n-butyl-N-methylamine

undec-10-ynoic acid

3,17β-dihydroxyestra-1,3,5(10)-trien-6-one 17-acetate 3-methyl ether

Downstream raw materials:

11-(3,17β-dihydroxy-estra-1,3,5(10)-triene-7α-yl)-undecanoic acid n-butyl-methyl-amide

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 153004-18-3 11-((6R,7S,8R,9S,13S,14S,17S)-6-Benzenesulfonyl-17-hydroxy-3-methoxy-13-methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthren-7-yl)-undecanoic acid butyl-methyl-amide

Send

Send

Metric Ton KG G Pound L ML

Send

Send