(2R,3S)-5,7-bis(benzyloxy)-2-(3,4-bis(benzyloxy)phenyl)chroman-3-yl acetate

Base Information

• Chemical Name: (2R,3S)-5,7-bis(benzyloxy)-2-(3,4-bis(benzyloxy)phenyl)chroman-3-yl acetate
• CAS No.: 20728-74-9
• Molecular Formula: C₄₅H₄₀O₇
• Molecular Weight: 692.808

Synonyms:(2R,3S)-5,7-bis(benzyloxy)-2-(3,4-bis(benzyloxy)phenyl)chroman-3-yl acetate

Chemical Property of (2R,3S)-5,7-bis(benzyloxy)-2-(3,4-bis(benzyloxy)phenyl)chroman-3-yl acetate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (2R,3S)-5,7-bis(benzyloxy)-2-(3,4-bis(benzyloxy)phenyl)chroman-3-yl acetate

There total 8 articles about (2R,3S)-5,7-bis(benzyloxy)-2-(3,4-bis(benzyloxy)phenyl)chroman-3-yl acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

acetic anhydride (108-24-7) + 5,7,3',4'-tetra-O-benzyl-(+)-catechin (20728-73-8) → (2R,3S)-5,7-bis(benzyloxy)-2-(3,4-bis(benzyloxy)phenyl)chroman-3-yl acetate (20728-74-9)

Guidance literature:

With pyridine; dmap; at 20 ℃;

DOI:10.1016/j.bmcl.2017.10.007

Reference yield: 71.0%

2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl trichloroacetimidate (92052-29-4) + 5,7,3',4'-tetra-O-benzyl-(+)-catechin (20728-73-8) → Acetic acid (2R,3R,4S,5R,6R)-4,5-diacetoxy-6-acetoxymethyl-2-[(2R,3S)-5,7-bis-benzyloxy-2-(3,4-bis-benzyloxy-phenyl)-chroman-3-yloxy]-tetrahydro-pyran-3-yl ester (908855-83-4) + (2R,3S)-5,7-bis(benzyloxy)-2-(3,4-bis(benzyloxy)phenyl)chroman-3-yl acetate (20728-74-9)

Guidance literature:

With trimethylsilyl trifluoromethanesulfonate; In dichloromethane; at -40 ℃; for 2h;

DOI:10.1021/ol0614976

Reference yield: 67.0%

C49H41NO10S + cesium acetate (3396-11-0) → C43H36O5 + (2R,3S)-5,7-bis(benzyloxy)-2-(3,4-bis(benzyloxy)phenyl)chroman-3-yl acetate (20728-74-9) + 5,7-bis-benzyloxy-2-(3,4-bis-benzyloxy-phenyl)-2H-chromene

Guidance literature:

With 18-crown-6 ether; In toluene; for 0.666667h; Reflux;

DOI:10.1021/acs.orglett.8b00873

upstream raw materials:

(+)-pentaacetylcatechin

benzyl chloride

2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl trichloroacetimidate

5,7,3',4'-tetra-O-benzyl-(+)-catechin

Downstream raw materials:

3-acetoxy-5,7,3',4'-tetra-O-benzyl-8-formylcatechin

C₇₀H₆₂O₁₈

5,7,3',4'-tetra-O-benzyl-(+)-catechin

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 20728-74-9 (2R,3S)-5,7-bis(benzyloxy)-2-(3,4-bis(benzyloxy)phenyl)chroman-3-yl acetate

Send

Send

Metric Ton KG G Pound L ML

Send

Send