Technology Process of Cyclohexanecarboxylic acid, 3,4-dihydroxy-, (1R,3S,4R)-rel- (9CI)
There total 7 articles about Cyclohexanecarboxylic acid, 3,4-dihydroxy-, (1R,3S,4R)-rel- (9CI) which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
1,2,5,6-tetrahydrobenzoic acid;
With
3-chloro-benzenecarboperoxoic acid;
In
tetrachloromethane;
at 20 ℃;
With
triethylamine;
In
tetrachloromethane;
for 4h;
Reflux;
With
hydrogenchloride;
In
tetrahydrofuran; water;
-
-
23477-88-5,31540-11-1,32746-99-9,50426-47-6,67068-73-9,67068-74-0,76704-84-2,333364-12-8
(+/-)-(1R*,3R*,4R*)-3,4-dihydroxycyclohexanecarboxylic acid
- Guidance literature:
-
With
potassium hydroxide; water;
In
tetrahydrofuran;
-
-
23477-88-5,31540-11-1,32746-99-9,50426-47-6,67068-73-9,67068-74-0,76704-84-2,333364-12-8
(+/-)-(1R*,3R*,4R*)-3,4-dihydroxycyclohexanecarboxylic acid
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: 3-chloro-benzenecarboperoxoic acid / tetrachloromethane / 4 h
1.2: 4 h / 65 °C
2.1: water; potassium hydroxide / tetrahydrofuran
With
water; 3-chloro-benzenecarboperoxoic acid; potassium hydroxide;
In
tetrahydrofuran; tetrachloromethane;