1,4-Dimorpholinobenzene

Base Information

• Chemical Name: 1,4-Dimorpholinobenzene
• CAS No.: 4096-22-4
• Molecular Formula: C14H20 N2 O2
• Molecular Weight: 248.325
• Hs Code.: 2934999090
• Mol file: 4096-22-4.mol

Synonyms:Morpholine,4,4'-p-phenylenedi- (7CI,8CI); 1,4-Dimorpholinobenzene;4,4'-(1,4-phenylene)bis[morpholine]

Chemical Property of 1,4-Dimorpholinobenzene

Chemical Property:

• Boiling Point: 444.8°Cat760mmHg
• Flash Point: 139.7°C
• PSA: 24.94000
• Density: 1.149g/cm³
• LogP: 1.48980

Purity/Quality:

99%min ^*data from raw suppliers

1,4-DIMORPHOLINOBENZENE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1,4-Dimorpholinobenzene

There total 19 articles about 1,4-Dimorpholinobenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

morpholine (110-91-8,99108-56-2) + para-dichlorobenzene (106-46-7,84348-21-0) → 4-[4-(morpholin-4-yl)phenyl]morpholine (4096-22-4)

Guidance literature:

With sodium t-butanolate; 1,3-bis[2,6-diisopropylphenyl]imidazolium chloride; Ni(PPh₃)2(phenyl)Br; In 1,4-dioxane; at 80 ℃;

DOI:10.1021/jo0709448

Reference yield: 84.0%

morpholine (110-91-8,99108-56-2) + 4-(4-(methylthio)phenyl)morpholine → 4-[4-(morpholin-4-yl)phenyl]morpholine (4096-22-4)

Guidance literature:

With bis(1,5-cyclooctadiene)nickel ⁽⁰⁾; lithium hexamethyldisilazane; 1,2-bis-(dicyclohexylphosphino)ethane; In toluene; at 100 ℃; for 12h;

DOI:10.1021/acscatal.0c00393

Reference yield: 78.8%

morpholine (110-91-8,99108-56-2) + 1.4-dibromobenzene (106-37-6) → 4-[4-(morpholin-4-yl)phenyl]morpholine (4096-22-4)

Guidance literature:

With C₃₀H₂₅BrN₃PPdS; potassium carbonate; In iso-butanol; at 100 ℃; for 24h; Inert atmosphere;

DOI:10.1016/j.tetlet.2012.12.070

upstream raw materials:

3-oxa-1,5-dichloropentane

1,4-phenylenediamine

cinnamoyl chloride

1,4-dimorpholinocyclohexa-1,3-diene

Refernces

• 1、 -. "Room-temperature phosphorescent material as well as preparation method and application thereof". Paragraph 0070-0073. . Retrieved 2021/09/21.
• 2、 Dang-Bao, Trung,Pradel, Christian,Favier, Isabelle,Gómez, Montserrat. "Making Copper(0) Nanoparticles in Glycerol: A Straightforward Synthesis for a Multipurpose Catalyst". . p. 2832 - 2846. Retrieved 2017/08/23.