Urea, N,N'-bis[[(5S)-2-oxo-3-[4-(3-oxo-4-Morpholinyl)phenyl]-5-oxazolidinyl]Methyl]-

Base Information Edit

Chemical Name:Urea, N,N'-bis[[(5S)-2-oxo-3-[4-(3-oxo-4-Morpholinyl)phenyl]-5-oxazolidinyl]Methyl]-
CAS No.:1365267-35-1
Molecular Formula:C₂₉H₃₂N₆O₉
Molecular Weight:608.608
Hs Code.:
Mol file:1365267-35-1.mol

Synonyms:N,N'-bis[{(5S)-2-oxo-3-[4-(3-oxomorpholin-4-yl)phenyl]-1,3-oxazolidin-5-yl}methyl]urea

Suppliers and Price of Urea, N,N'-bis[[(5S)-2-oxo-3-[4-(3-oxo-4-Morpholinyl)phenyl]-5-oxazolidinyl]Methyl]-

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
N,N’-Bis[Des(5-chloro-2-carvoxythienyl)Rivaroxaban]Urea
250mg
$ 1115.00

Total 16 raw suppliers

Chemical Property of Urea, N,N'-bis[[(5S)-2-oxo-3-[4-(3-oxo-4-Morpholinyl)phenyl]-5-oxazolidinyl]Methyl]- Edit

Chemical Property:

Melting Point:>240°C (dec.)
Boiling Point:993.6±65.0 °C(Predicted)
PKA:13.02±0.46(Predicted)
Density:1.423±0.06 g/cm3(Predicted)
Storage Temp.:Refrigerator
Solubility.:DMSO (Slightly, Sonicated), Methanol (Very Slightly, Heated)

Purity/Quality:

98%min ^*data from raw suppliers

N,N’-Bis[Des(5-chloro-2-carvoxythienyl)Rivaroxaban]Urea ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Uses N,N’-Bis[Des(5-chloro-2-carvoxythienyl) Rivaroxaban] Urea is an impurity of Rivaroxaban (R538000), a novel antithrombotic agent. A highly potent and selective, direct FXa inhibitor.

Technology Process of Urea, N,N'-bis[[(5S)-2-oxo-3-[4-(3-oxo-4-Morpholinyl)phenyl]-5-oxazolidinyl]Methyl]-

There total 2 articles about Urea, N,N'-bis[[(5S)-2-oxo-3-[4-(3-oxo-4-Morpholinyl)phenyl]-5-oxazolidinyl]Methyl]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 38.8%

: 446292-10-0,1411775-06-8
4-[4-[(5S)-5-(aminomethyl)-2-oxo-1,3-oxazolidin-3-yl]phenyl]morpholine-3-one

: 32315-10-9
bis(trichloromethyl) carbonate

: 1365267-35-1
N,N'-bis[{(5S)-2-oxo-3-[4-(3-oxomorpholin-4-yl)phenyl]-1,3-oxazolidin-5-yl}methyl]urea

Guidance literature:: 4-[4-[(5S)-5-(aminomethyl)-2-oxo-1,3-oxazolidin-3-yl]phenyl]morpholine-3-one; bis(trichloromethyl) carbonate; With triethylamine; In tetrahydrofuran; at 20 ℃; Cooling;

With sodium carbonate; In tetrahydrofuran;