optically inactive (3-ethoxycarbonyl-2-oxo-cyclohexyl)-acetic acid

Base Information

• Chemical Name: optically inactive (3-ethoxycarbonyl-2-oxo-cyclohexyl)-acetic acid
• CAS No.: 408511-90-0
• Molecular Formula: C₁₁H₁₆O₅
• Molecular Weight: 228.245
• Mol file: 408511-90-0.mol

Synonyms:optically inactive (3-ethoxycarbonyl-2-oxo-cyclohexyl)-acetic acid

Chemical Property of optically inactive (3-ethoxycarbonyl-2-oxo-cyclohexyl)-acetic acid

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

Useful:

Technology Process of optically inactive (3-ethoxycarbonyl-2-oxo-cyclohexyl)-acetic acid

There total 2 articles about optically inactive (3-ethoxycarbonyl-2-oxo-cyclohexyl)-acetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-ethoxycarbonyl-6-ethoxycarbonylmethylcyclohexanone (412321-62-1) → optically inactive (3-ethoxycarbonyl-2-oxo-cyclohexyl)-acetic acid (408511-90-0)

Guidance literature:

2-ethoxycarbonyl-6-ethoxycarbonylmethylcyclohexanone; With potassium hydroxide; ethanol; at 20 ℃; for 1.5h;

With hydrogenchloride; In water; at 0 ℃;

Reference yield:

→ optically inactive (3-ethoxycarbonyl-2-oxo-cyclohexyl)-acetic acid (408511-90-0)

Guidance literature:

With potassium hydroxide;

DOI:10.1021/ja01628a069

Reference yield:

optically inactive (3-ethoxycarbonyl-2-oxo-cyclohexyl)-acetic acid (408511-90-0) → (+/-)-(3-ethoxycarbonyl-2-hydroxy-cyclohex-enyl)-acetic acid

Guidance literature:

With diethyl ether; boron trifluoride; acetic acid;

DOI:10.1021/ja01628a069

upstream raw materials:

2-ethoxycarbonyl-6-ethoxycarbonylmethylcyclohexanone