6-Amino-5-methylpyridine-3-sulfonamide

Base Information

Chemical Name:6-Amino-5-methylpyridine-3-sulfonamide
CAS No.:329945-05-3
Molecular Formula:C6H9 N3 O2 S
Molecular Weight:187.21956
Hs Code.:
DSSTox Substance ID:DTXSID201284982
Mol file:329945-05-3.mol

Synonyms:6-amino-5-methylpyridine-3-sulfonamide;329945-05-3;3-Pyridinesulfonamide,6-amino-5-methyl-(9CI);6-amino-5-methyl-3-pyridinesulfonamide;Oprea1_579664;SCHEMBL5626144;DTXSID201284982;AKOS006279643;3-pyridinesulfonamide,6-amino-5-methyl-;EN300-79289

Suppliers and Price of 6-Amino-5-methylpyridine-3-sulfonamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
6-AMINO-5-METHYL-PYRIDINE-3-SULFONIC ACID AMIDE 95.00%
5MG
$ 504.49

AK Scientific
6-Amino-5-methylpyridine-3-sulfonamide
2.5g
$ 1116.00

AK Scientific
6-Amino-5-methylpyridine-3-sulfonamide
1g
$ 619.00

AK Scientific
6-Amino-5-methylpyridine-3-sulfonamide
100mg
$ 240.00

Total 1 raw suppliers

Chemical Property of 6-Amino-5-methylpyridine-3-sulfonamide

Chemical Property:

PSA：108.18000
LogP:1.33080
XLogP3:-0.6
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:1
Exact Mass:187.04154771
Heavy Atom Count:12
Complexity:246

Purity/Quality:: 6-AMINO-5-METHYL-PYRIDINE-3-SULFONIC ACID AMIDE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC(=CN=C1N)S(=O)(=O)N

Technology Process of 6-Amino-5-methylpyridine-3-sulfonamide

There total 3 articles about 6-Amino-5-methylpyridine-3-sulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 45.0%

: 874889-40-4
6-{[(E)-(dimethylamino)methylidene]amino}-5-methyl-3-pyridinesulfonic acid

: 329945-05-3
6-amino-5-methyl-3-pyridinesulfonamide

Guidance literature:: 6-{[(E)-(dimethylamino)methylidene]amino}-5-methyl-3-pyridinesulfonic acid; With phosphorus pentachloride; at 130 ℃; for 1.5h;

With ammonium hydroxide; for 4h; Heating;
DOI:10.1021/jm050670l

Reference yield:

: 40741-48-8
6-amino-5-methyl-3-pyridinesulfonic acid

: 329945-05-3
6-amino-5-methyl-3-pyridinesulfonamide

Guidance literature:: Multi-step reaction with 2 steps

1.1: 77 percent / thionyl chloride / dimethylformamide / 0.67 h / 20 °C

2.1: PCl₅ / 1.5 h / 130 °C

2.2: 45 percent / aq. NH₃ / 4 h / Heating

With thionyl chloride; phosphorus pentachloride; In N,N-dimethyl-formamide;
DOI:10.1021/jm050670l

Reference yield:

: 1603-40-3
3-methylpyridin-2-ylamine

: 329945-05-3
6-amino-5-methyl-3-pyridinesulfonamide

Guidance literature:: Multi-step reaction with 3 steps

1.1: 50 percent / H₂SO₄ / 20 h / 160 °C

2.1: 77 percent / thionyl chloride / dimethylformamide / 0.67 h / 20 °C

3.1: PCl₅ / 1.5 h / 130 °C

3.2: 45 percent / aq. NH₃ / 4 h / Heating

With thionyl chloride; phosphorus pentachloride; sulfuric acid; In N,N-dimethyl-formamide;
DOI:10.1021/jm050670l