(1r,4r)-ethyl 4-(4-amino-3-fluorophenyl)cyclohexanecarboxylate hydrochloride

Base Information

Chemical Name:(1r,4r)-ethyl 4-(4-amino-3-fluorophenyl)cyclohexanecarboxylate hydrochloride
CAS No.:1231895-51-4
Molecular Formula:C₁₅H₂₀FNO₂*ClH
Molecular Weight:301.789
Hs Code.:

Synonyms:(1r,4r)-ethyl 4-(4-amino-3-fluorophenyl)cyclohexanecarboxylate hydrochloride

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (1r,4r)-ethyl 4-(4-amino-3-fluorophenyl)cyclohexanecarboxylate hydrochloride

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Technology Process of (1r,4r)-ethyl 4-(4-amino-3-fluorophenyl)cyclohexanecarboxylate hydrochloride

There total 2 articles about (1r,4r)-ethyl 4-(4-amino-3-fluorophenyl)cyclohexanecarboxylate hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 1231895-52-5
(1s,4s)-ethyl 4-(4-(tert-butoxycarbonylamino)-3-fluorophenyl)cyclohexanecarboxylate

: 1231895-51-4
(1r,4r)-ethyl 4-(4-amino-3-fluorophenyl)cyclohexanecarboxylate hydrochloride

Guidance literature:: (1s,4s)-ethyl 4-(4-(tert-butoxycarbonylamino)-3-fluorophenyl)cyclohexanecarboxylate; With potassium tert-butylate; In tert-butyl alcohol; for 4h; Inert atmosphere;

With hydrogenchloride; water; ammonium chloride; In tert-butyl alcohol; pH=1;

With hydrogenchloride; In 1,4-dioxane; ethanol; at 20 ℃; for 72h; Product distribution / selectivity;