3-Deoxy-1,2:5,6-di-O-isopropylidene-3-C-<2-oxo-5-<(tert-butyldiphenylsilyl)oxy>pentyl>-α-D-allofuranose

Base Information

• Chemical Name: 3-Deoxy-1,2:5,6-di-O-isopropylidene-3-C-<2-oxo-5-<(tert-butyldiphenylsilyl)oxy>pentyl>-α-D-allofuranose
• CAS No.: 143135-28-8
• Molecular Formula: C₃₃H₄₆O₇Si
• Molecular Weight: 582.81

Synonyms:3-Deoxy-1,2:5,6-di-O-isopropylidene-3-C-<2-oxo-5-<(tert-butyldiphenylsilyl)oxy>pentyl>-α-D-allofuranose

Chemical Property of 3-Deoxy-1,2:5,6-di-O-isopropylidene-3-C-<2-oxo-5-<(tert-butyldiphenylsilyl)oxy>pentyl>-α-D-allofuranose

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-Deoxy-1,2:5,6-di-O-isopropylidene-3-C-<2-oxo-5-<(tert-butyldiphenylsilyl)oxy>pentyl>-α-D-allofuranose

There total 5 articles about 3-Deoxy-1,2:5,6-di-O-isopropylidene-3-C-<2-oxo-5-<(tert-butyldiphenylsilyl)oxy>pentyl>-α-D-allofuranose which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

3-Deoxy-3-C-<2-hydroxy-5-<(tert-butyldiphenylsilyl)oxy>pentyl>-1,2:5,6-di-O-isopropylidene-α-D-allofuranose (143135-27-7,143135-38-0) → 3-Deoxy-1,2:5,6-di-O-isopropylidene-3-C-<2-oxo-5-<(tert-butyldiphenylsilyl)oxy>pentyl>-α-D-allofuranose (143135-28-8)

Guidance literature:

With 4 A molecular sieve; pyridinium chlorochromate; In dichloromethane; for 1h;

DOI:10.1016/S0040-4020(01)80440-3

Reference yield:

1,2;5,6-di-O-isopropylidene-3-(2-hydroxyethyl)-α-D-allofuranoside (18427-19-5) → 3-Deoxy-1,2:5,6-di-O-isopropylidene-3-C-<2-oxo-5-<(tert-butyldiphenylsilyl)oxy>pentyl>-α-D-allofuranose (143135-28-8)

Guidance literature:

Multi-step reaction with 5 steps

1: PCC, molecular sieves 4A / CH₂Cl₂ / 0.75 h

2: 87 percent / tetrahydrofuran / 0.75 h / Ambient temperature

3: 1) BH₃*THF, 2) 35percent aq. H₂O₂, 3M aq. NaOH / 1) THF, 0 deg C, 3h, 2) water, 30 min

4: imidazole / dimethylformamide / 3 h

5: 98 percent / PCC, molecular sieve 4A / CH₂Cl₂ / 1 h

With 1H-imidazole; sodium hydroxide; borane-THF; 4 A molecular sieve; dihydrogen peroxide; pyridinium chlorochromate; In tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide;

DOI:10.1016/S0040-4020(01)80440-3

Reference yield:

5-[(3aR,5S,6R,6aR)-5-((R)-2,2-Dimethyl-[1,3]dioxolan-4-yl)-2,2-dimethyl-tetrahydro-furo[2,3-d][1,3]dioxol-6-yl]-pentane-1,4-diol (143135-48-2,143135-49-3) → 3-Deoxy-1,2:5,6-di-O-isopropylidene-3-C-<2-oxo-5-<(tert-butyldiphenylsilyl)oxy>pentyl>-α-D-allofuranose (143135-28-8)

Guidance literature:

Multi-step reaction with 2 steps

1: imidazole / dimethylformamide / 3 h

2: 98 percent / PCC, molecular sieve 4A / CH₂Cl₂ / 1 h

With 1H-imidazole; 4 A molecular sieve; pyridinium chlorochromate; In dichloromethane; N,N-dimethyl-formamide;

DOI:10.1016/S0040-4020(01)80440-3

upstream raw materials:

3-Deoxy-3-C-<2-hydroxy-5-<(tert-butyldiphenylsilyl)oxy>pentyl>-1,2:5,6-di-O-isopropylidene-α-D-allofuranose

1,2;5,6-di-O-isopropylidene-3-(2-hydroxyethyl)-α-D-allofuranoside

5-[(3aR,5S,6R,6aR)-5-((R)-2,2-Dimethyl-[1,3]dioxolan-4-yl)-2,2-dimethyl-tetrahydro-furo[2,3-d][1,3]dioxol-6-yl]-pentane-1,4-diol

[(3aR,5S,6R,6aR)-5-((R)-2,2-Dimethyl-[1,3]dioxolan-4-yl)-2,2-dimethyl-tetrahydro-furo[2,3-d][1,3]dioxol-6-yl]-acetaldehyde

Downstream raw materials:

5-(tert-Butyl-diphenyl-silanyloxy)-1-[(3aR,5S,6R,6aR)-5-((R)-1,2-dihydroxy-ethyl)-2,2-dimethyl-tetrahydro-furo[2,3-d][1,3]dioxol-6-yl]-pentan-2-one

(1R,3S,8R,9R)-11,11-Dimethyl-5-<2-(tert-butyldiphenylsiloxy)ethyl>-2,10,12-trioxatricyclo<7.3.0.0^3,8>dodec-4-en-6-one

3-Deoxy-1,2-O-isopropylidene-3-C-<<2-oxo-5-(tert-butyldiphenylsilyl)oxy>pentyl>-α-D-1,4-dialdo-ribofuranose

(1R,3R,4R,8R,9R)-4,11,11-Trimethyl-5-<2-(tert-butyldiphenylsilyl)oxyethyl>-2,10,12-trioxatricyclo<7.3.0.0^3,8>dodecan-6-one

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 143135-28-8 3-Deoxy-1,2:5,6-di-O-isopropylidene-3-C-<2-oxo-5-<(tert-butyldiphenylsilyl)oxy>pentyl>-α-D-allofuranose

Send

Send

Metric Ton KG G Pound L ML

Send

Send