Monastrol

Base Information

Chemical Name:Monastrol
CAS No.:329689-23-8
Molecular Formula:C14H16 N2 O3 S
Molecular Weight:292.359
Hs Code.:
NSC Number:716782
DSSTox Substance ID:DTXSID10388124,DTXSID501317756
Nikkaji Number:J1.229.496D
Wikipedia:Monastrol
Wikidata:Q6898425
Pharos Ligand ID:S7LS593LZTM7
ChEMBL ID:CHEMBL236789
Mol file:329689-23-8.mol

Synonyms:monastrol

Suppliers and Price of Monastrol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
Monastrol
10mg
$ 602.00

TRC
Monastrol
5mg
$ 85.00

TRC
Monastrol
50mg
$ 390.00

Tocris
Monastrol ≥98%(HPLC)
50
$ 818.00

Sigma-Aldrich
Monastrol ≥98% (HPLC), solid
1 mg
$ 115.00

Sigma-Aldrich
Monastrol ≥98% (HPLC), solid
5 mg
$ 392.00

DC Chemicals
Monastrol >98%
1 g
$ 1600.00

DC Chemicals
Monastrol >98%
250 mg
$ 800.00

Crysdot
Monastrol 98+%
100mg
$ 317.00

Crysdot
Monastrol 98+%
25mg
$ 119.00

Total 15 raw suppliers

Chemical Property of Monastrol

Chemical Property:

Vapor Pressure:2.13E-08mmHg at 25°C
Melting Point:190-193℃ (ethanol )
Refractive Index:1.648
Boiling Point:441.3°C at 760 mmHg
PKA:9.63±0.10(Predicted)
Flash Point:220.7°C
PSA：109.72000
Density:1.34±0.1 g/cm3 (20 ºC 760 Torr)
LogP:1.92380
Storage Temp.:under inert gas (nitrogen or Argon) at 2-8°C
Sensitive.:Light Sensitive
Solubility.:DMSO (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly, Heated)
XLogP3:1.6
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:292.08816355
Heavy Atom Count:20
Complexity:436

Purity/Quality:

99%, ^*data from raw suppliers

Monastrol ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)C1=C(NC(=S)NC1C2=CC(=CC=C2)O)C
Uses Monastrol is a small molecule that inhibits mitotic kinesin Eg5 and arrests cells in mitosis with monopolar spindles (1, 2).Monastrol is an anticancer agent against MCF-7 tumor cells (3).

Technology Process of Monastrol

There total 5 articles about Monastrol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%