N-((1R,2R)-2-Amino-1,2-diphenyl-ethyl)-4-((S)-6-oxo-tetrahydro-pyran-2-yl)-butyramide

Base Information

Chemical Name:N-((1R,2R)-2-Amino-1,2-diphenyl-ethyl)-4-((S)-6-oxo-tetrahydro-pyran-2-yl)-butyramide
CAS No.:124468-89-9
Molecular Formula:C₂₃H₂₈N₂O₃
Molecular Weight:380.487
Hs Code.:

Synonyms:N-((1R,2R)-2-Amino-1,2-diphenyl-ethyl)-4-((S)-6-oxo-tetrahydro-pyran-2-yl)-butyramide

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Chemical Property of N-((1R,2R)-2-Amino-1,2-diphenyl-ethyl)-4-((S)-6-oxo-tetrahydro-pyran-2-yl)-butyramide

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Technology Process of N-((1R,2R)-2-Amino-1,2-diphenyl-ethyl)-4-((S)-6-oxo-tetrahydro-pyran-2-yl)-butyramide

There total 4 articles about N-((1R,2R)-2-Amino-1,2-diphenyl-ethyl)-4-((S)-6-oxo-tetrahydro-pyran-2-yl)-butyramide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

: 124468-87-7
(2R,3R)-9-Hydroxy-2,3-diphenyl-1,4-diaza-cyclotridecane-5,13-dione

: 124468-89-9
N-((1R,2R)-2-Amino-1,2-diphenyl-ethyl)-4-((S)-6-oxo-tetrahydro-pyran-2-yl)-butyramide

Guidance literature:: With trifluoroacetic acid; In dichloromethane; for 12h; Ambient temperature;
DOI:10.1246/cl.1999.889

Reference yield:

: 35132-20-8
(R,R)-1,2-diphenylethylenediamine

: 124468-89-9
N-((1R,2R)-2-Amino-1,2-diphenyl-ethyl)-4-((S)-6-oxo-tetrahydro-pyran-2-yl)-butyramide

Guidance literature:: Multi-step reaction with 3 steps

1: Et₃N / CH₂Cl₂

2: KOH / tetrahydrofuran

3: 79 percent / trifluoroacetic acid / CH₂Cl₂ / 12 h / Ambient temperature

With potassium hydroxide; triethylamine; trifluoroacetic acid; In tetrahydrofuran; dichloromethane;
DOI:10.1246/cl.1999.889

Reference yield:

: 131702-55-1
5-acetoxynonanedioyl dichloride

: 124468-89-9
N-((1R,2R)-2-Amino-1,2-diphenyl-ethyl)-4-((S)-6-oxo-tetrahydro-pyran-2-yl)-butyramide

Guidance literature:: Multi-step reaction with 3 steps

1: Et₃N / CH₂Cl₂

2: KOH / tetrahydrofuran

3: 79 percent / trifluoroacetic acid / CH₂Cl₂ / 12 h / Ambient temperature

With potassium hydroxide; triethylamine; trifluoroacetic acid; In tetrahydrofuran; dichloromethane;
DOI:10.1246/cl.1999.889