Tetracyclo[3.2.0.02,7.04,6]heptane-1-carboxylic acid, methyl ester,

Base Information

• Chemical Name: Tetracyclo[3.2.0.02,7.04,6]heptane-1-carboxylic acid, methyl ester,
• CAS No.: 327035-52-9
• Molecular Formula: C₉H₁₀O₂
• Molecular Weight: 150.177
• Mol file: 327035-52-9.mol

Synonyms:Tetracyclo[3.2.0.02,7.04,6]heptane-1-carboxylic acid, methyl ester, (1S,2R,4S,5S,6R,7S)-

Chemical Property of Tetracyclo[3.2.0.02,7.04,6]heptane-1-carboxylic acid, methyl ester,

Chemical Property:

• Boiling Point: 204.6±8.0 °C(Predicted)
• PSA: 26.30000
• Density: 1.507±0.06 g/cm3(Predicted)
• LogP: 0.67130

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Tetracyclo[3.2.0.02,7.04,6]heptane-1-carboxylic acid, methyl ester,

There total 7 articles about Tetracyclo[3.2.0.02,7.04,6]heptane-1-carboxylic acid, methyl ester, which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

(-)-methyl bicyclo[2.2.1]hepta-2,5-diene-2-carboxylate → (+)-methyl quadricyclane-1-carboxylate (327035-53-0,327035-52-9)

Guidance literature:

for 2.11667h; Conversion of starting material; Irradiation with LPL 290 nm;

Reference yield: 81.0%

methyl bicyclo[2.2.1]hepta-2,5-diene-2-carboxylate (3604-36-2) → Tetracyclo<3.2.0.02,7.04,6>heptan-1-carbonsaeure-methylester (24161-47-5,327035-53-0,327035-52-9)

Guidance literature:

In acetonitrile; Photolysis;

DOI:10.1039/b100751n

Reference yield: 68.0%

diazomethane (186581-53-3,908094-01-9,334-88-3) + Tetracyclo<3.2.0.02,7.04,6>heptan-1-carbonsaeure (111233-95-5) → Tetracyclo<3.2.0.02,7.04,6>heptan-1-carbonsaeure-methylester (24161-47-5,327035-53-0,327035-52-9)

Guidance literature:

In diethyl ether;

upstream raw materials:

diazomethane

Tetracyclo<3.2.0.0^2,7.0^4,6>heptan-1-carbonsaeure

Tetracyclo<3.2.0.0^2,7.0^4,6>hept-1-yllithium

methyl chloroformate

Refernces

• 1、 Nishino,Nakamura,Inoue. "Synchronous enantiomeric enrichment of both reactant and product by absolute asymmetric synthesis using circularly polarized light. Part 1. Theoretical and experimental verification of the asymmetric photoisomerization of methyl norbornadiene-2-carboxylate to methyl quadricyclane-1-carboxylate". . p. 1693 - 1700. Retrieved 2007/10/03.
• 2、 Heywang, Ulrich,Szeimies, Guenter. "Experiments towards the Generation of 1,5- and 2,3-Didehydroquadricyclanes". . p. 121 - 131. Retrieved 2007/10/02.