Technology Process of C19H22O5
There total 5 articles about C19H22O5 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH2Cl2; caesium carbonate;
In
water; toluene;
at 100 ℃;
for 18h;
Inert atmosphere;
DOI:10.1016/j.bmc.2012.11.056
- Guidance literature:
-
Multi-step reaction with 3 steps
1: palladium diacetate / diethyl ether / -15 - 20 °C
2: potassium hydrogenfluoride / methanol; water / 48 h / 80 °C
3: dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH2Cl2; caesium carbonate / water; toluene / 18 h / 100 °C / Inert atmosphere
With
dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH2Cl2; potassium hydrogenfluoride; palladium diacetate; caesium carbonate;
In
methanol; diethyl ether; water; toluene;
1: |Simmons-Smith Cyclopropanation / 3: |Suzuki-Miyaura Coupling;
DOI:10.1016/j.bmc.2012.11.056
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: Triisopropyl borate; tert.-butyl lithium / tetrahydrofuran; pentane / 0.17 h / -78 °C
1.2: 21.75 h / -78 - 20 °C
2.1: palladium diacetate / diethyl ether / -15 - 20 °C
3.1: potassium hydrogenfluoride / methanol; water / 48 h / 80 °C
4.1: dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH2Cl2; caesium carbonate / water; toluene / 18 h / 100 °C / Inert atmosphere
With
dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH2Cl2; potassium hydrogenfluoride; Triisopropyl borate; tert.-butyl lithium; palladium diacetate; caesium carbonate;
In
tetrahydrofuran; methanol; diethyl ether; water; toluene; pentane;
2.1: |Simmons-Smith Cyclopropanation / 4.1: |Suzuki-Miyaura Coupling;
DOI:10.1016/j.bmc.2012.11.056
