Technology Process of 3-ethyl-1,2,3,4-tetrahydro-3-(phenylmethyl)pyrido<3,4-e>-1,2,4-triazine hydrochloride
There total 5 articles about 3-ethyl-1,2,3,4-tetrahydro-3-(phenylmethyl)pyrido<3,4-e>-1,2,4-triazine hydrochloride which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
hydrogenchloride;
In
ethanol;
1.) overnight, 2.) reflux, 1 h;
DOI:10.1021/jm00131a010
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 87 percent / PCl5, POCl3 / 6 h / 130 - 140 °C
2: 77 percent / N2H4*H2O / ethanol / 1.) 0 deg C, 0.75 h, 2.) 25 deg C, 3.5 h
3: 4.9 g / H2 / 5percent Pd/C / aq. ethanol
4: 83 percent / HCl / ethanol / 1.) overnight, 2.) reflux, 1 h
With
hydrogenchloride; phosphorus pentachloride; hydrogen; hydrazine hydrate; trichlorophosphate;
palladium on activated charcoal;
In
ethanol;
DOI:10.1021/jm00131a010
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 72 percent / HNO3, H2SO4, SO3 / 1 h / Heating
2: 87 percent / PCl5, POCl3 / 6 h / 130 - 140 °C
3: 77 percent / N2H4*H2O / ethanol / 1.) 0 deg C, 0.75 h, 2.) 25 deg C, 3.5 h
4: 4.9 g / H2 / 5percent Pd/C / aq. ethanol
5: 83 percent / HCl / ethanol / 1.) overnight, 2.) reflux, 1 h
With
hydrogenchloride; phosphorus pentachloride; sulfuric acid; sulfur trioxide; hydrogen; nitric acid; hydrazine hydrate; trichlorophosphate;
palladium on activated charcoal;
In
ethanol;
DOI:10.1021/jm00131a010
