Technology Process of 5-Pyrimidinepropanoic acid, alpha-aminohexahydro-1-methyl-2,4-dioxo-, (alphaS,5S)- (9CI)
There total 6 articles about 5-Pyrimidinepropanoic acid, alpha-aminohexahydro-1-methyl-2,4-dioxo-, (alphaS,5S)- (9CI) which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
hydrogen;
palladium on activated charcoal;
In
acetic acid;
at 20 ℃;
for 1h;
- Guidance literature:
-
Multi-step reaction with 6 steps
1: aq. HCl / methanol / 0.5 h / 20 °C
2: aq. methanol / 0.25 h / 20 °C
3: 99 percent / NaBH4 / acetic acid / 0.42 h
4: 86 percent / AcOH / methanol / 16 h / 20 °C
5: 90 percent / NaH / tetrahydrofuran / 0.5 h / 20 °C
6: H2 / 10 percent Pd/C / acetic acid / 1 h / 20 °C
With
hydrogenchloride; sodium tetrahydroborate; hydrogen; sodium hydride; acetic acid;
palladium on activated charcoal;
In
tetrahydrofuran; methanol; acetic acid;
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 99 percent / NaBH4 / acetic acid / 0.42 h
2: 86 percent / AcOH / methanol / 16 h / 20 °C
3: 90 percent / NaH / tetrahydrofuran / 0.5 h / 20 °C
4: H2 / 10 percent Pd/C / acetic acid / 1 h / 20 °C
With
sodium tetrahydroborate; hydrogen; sodium hydride; acetic acid;
palladium on activated charcoal;
In
tetrahydrofuran; methanol; acetic acid;