2,5-Thiazoledimethanol

Base Information

Chemical Name:2,5-Thiazoledimethanol
CAS No.:326850-61-7
Molecular Formula:C₅H₇NO₂S
Molecular Weight:145.182
Hs Code.:
DSSTox Substance ID:DTXSID40435938
Wikidata:Q82251080
Mol file:326850-61-7.mol

Synonyms:2,5-Thiazoledimethanol;326850-61-7;thiazole-2,5-diyldimethanol;SCHEMBL2956791;DTXSID40435938;2,5-di(hydroxymethyl)-1,3-thiazole

Suppliers and Price of 2,5-Thiazoledimethanol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of 2,5-Thiazoledimethanol

Chemical Property:

PSA：81.59000
LogP:0.12770
XLogP3:-0.7
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:145.01974964
Heavy Atom Count:9
Complexity:91

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=C(SC(=N1)CO)CO

Technology Process of 2,5-Thiazoledimethanol

There total 6 articles about 2,5-Thiazoledimethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

: 2-(hydroxymethyl)-1,3-thiazole-5-carbaldehyde

: 326850-61-7
2,5-di(hydroxymethyl)-1,3-thiazole

Guidance literature:: With sodium tetrahydroborate; In tetrahydrofuran; methanol; at 5 ℃; for 9h;
DOI:10.1134/S1070363215080113

Reference yield: 69.0%

: 5-(hydroxymethyl)-1,3-thiazole-2-carbaldehyde

: 326850-61-7
2,5-di(hydroxymethyl)-1,3-thiazole

Guidance literature:: With sodium tetrahydroborate; In tetrahydrofuran; methanol; at 5 ℃; for 9h;
DOI:10.1134/S1070363215080113

Reference yield:

: 1080060-60-1
2-(1,3-dioxolan-2-yl)-1,3-thiazole-5-carbaldehyde

: 326850-61-7
2,5-di(hydroxymethyl)-1,3-thiazole

Guidance literature:: Multi-step reaction with 3 steps

1: sodium tetrahydroborate

2: water; toluene-4-sulfonic acid / acetonitrile / 9 h / Reflux

3: sodium tetrahydroborate / tetrahydrofuran; methanol / 9 h / 5 °C

With sodium tetrahydroborate; water; toluene-4-sulfonic acid; In tetrahydrofuran; methanol; acetonitrile;
DOI:10.1134/S1070363215080113