(E)-11-(4-(2-(2-(tetrahydro-2H-pyran-2-yloxy)ethoxy)ethyl)piperazin-1-yl)dibenzo[b,f][1,4]thiazepine

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Chemical Name:(E)-11-(4-(2-(2-(tetrahydro-2H-pyran-2-yloxy)ethoxy)ethyl)piperazin-1-yl)dibenzo[b,f][1,4]thiazepine
CAS No.:848888-35-7
Molecular Formula:C₂₆H₃₃N₃O₃S
Molecular Weight:467.632
Hs Code.:

Synonyms:(E)-11-(4-(2-(2-(tetrahydro-2H-pyran-2-yloxy)ethoxy)ethyl)piperazin-1-yl)dibenzo[b,f][1,4]thiazepine

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Chemical Property of (E)-11-(4-(2-(2-(tetrahydro-2H-pyran-2-yloxy)ethoxy)ethyl)piperazin-1-yl)dibenzo[b,f][1,4]thiazepine

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Technology Process of (E)-11-(4-(2-(2-(tetrahydro-2H-pyran-2-yloxy)ethoxy)ethyl)piperazin-1-yl)dibenzo[b,f][1,4]thiazepine

There total 1 articles about (E)-11-(4-(2-(2-(tetrahydro-2H-pyran-2-yloxy)ethoxy)ethyl)piperazin-1-yl)dibenzo[b,f][1,4]thiazepine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 40.0%

: 17739-45-6,59146-56-4
2-(2-bromoethoxy)tetrahydropyran

: 329216-67-3
O-Dealkyl Quetiapine

: 848888-35-7
(E)-11-(4-(2-(2-(tetrahydro-2H-pyran-2-yloxy)ethoxy)ethyl)piperazin-1-yl)dibenzo[b,f][1,4]thiazepine

Guidance literature:: With tetra(n-butyl)ammonium hydrogensulfate; sodium hydroxide; at 60 ℃; for 24h;

Reference yield: 78.0%

: 848888-35-7
(E)-11-(4-(2-(2-(tetrahydro-2H-pyran-2-yloxy)ethoxy)ethyl)piperazin-1-yl)dibenzo[b,f][1,4]thiazepine

: 111974-69-7
Quetiapine

Guidance literature:: (E)-11-(4-(2-(2-(tetrahydro-2H-pyran-2-yloxy)ethoxy)ethyl)piperazin-1-yl)dibenzo[b,f][1,4]thiazepine; With hydrogenchloride; water; at 20 ℃; for 4h;

With potassium carbonate; In water; pH=9;