(2S,3S)-ethyl 3-(tert-butoxycarbonylamino)-2-(4-chlorobenzoyl)-2-fluoro-3-p-tolylpropanoate

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Chemical Name:(2S,3S)-ethyl 3-(tert-butoxycarbonylamino)-2-(4-chlorobenzoyl)-2-fluoro-3-p-tolylpropanoate
CAS No.:1192024-47-7
Molecular Formula:C₂₄H₂₇ClFNO₅
Molecular Weight:463.933
Hs Code.:

Synonyms:(2S,3S)-ethyl 3-(tert-butoxycarbonylamino)-2-(4-chlorobenzoyl)-2-fluoro-3-p-tolylpropanoate

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Chemical Property of (2S,3S)-ethyl 3-(tert-butoxycarbonylamino)-2-(4-chlorobenzoyl)-2-fluoro-3-p-tolylpropanoate

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Technology Process of (2S,3S)-ethyl 3-(tert-butoxycarbonylamino)-2-(4-chlorobenzoyl)-2-fluoro-3-p-tolylpropanoate

There total 1 articles about (2S,3S)-ethyl 3-(tert-butoxycarbonylamino)-2-(4-chlorobenzoyl)-2-fluoro-3-p-tolylpropanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: ethyl 2-fluoro-3-oxo-3-(p-chlorophenyl)propionate

: 479423-39-7
4-methylbenzaldehyde N-(tert-butoxycarbonyl)imine

: ethyl 3-(tert-butoxycarbonylamino)-2-(4-chlorobenzoyl)-2-fluoro-3-p-tolylpropanoate

: 1192024-47-7
(2S,3S)-ethyl 3-(tert-butoxycarbonylamino)-2-(4-chlorobenzoyl)-2-fluoro-3-p-tolylpropanoate

Guidance literature:: With (S)-1-(3,5-bis(trifluoromethyl)phenyl)-3-(1-(diethylamino)-3-(1H-indol-3-yl)propan-2-yl)thiourea; In toluene; at -50 ℃; for 24h; optical yield given as %de; enantioselective reaction;
DOI:10.1002/anie.200903635