C₁₈H₁₄FNO₃S

Base Information

• Chemical Name: C₁₈H₁₄FNO₃S
• CAS No.: 774244-06-3
• Molecular Formula: C₁₈H₁₄FNO₃S
• Molecular Weight: 343.378
• Mol file: 774244-06-3.mol

Synonyms:C₁₈H₁₄FNO₃S

Chemical Property of C₁₈H₁₄FNO₃S

Chemical Property:

Purity/Quality:

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Technology Process of C₁₈H₁₄FNO₃S

There total 1 articles about C₁₈H₁₄FNO₃S which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

benzothiophene-2-carboxylic acid chloride (39827-11-7) + (R)-2-amino-3-(3-fluorophenyl)propionic acid (110117-84-5,2629-54-1) → C18H14FNO3S (774244-06-3)

Guidance literature:

With sodium carbonate; In water; at 0 - 20 ℃; for 15h;

Reference yield: 22.5%

C18H14FNO3S (774244-06-3) → C18H16FNO2S (774244-13-2)

Guidance literature:

C₁₈H₁₄FNO₃S; With borane-THF; In tetrahydrofuran; at 0 - 25 ℃; for 15h;

With sodium hydrogencarbonate; In water; for 3h;

upstream raw materials:

benzothiophene-2-carboxylic acid chloride

(R)-2-amino-3-(3-fluorophenyl)propionic acid

Downstream raw materials:

C₁₈H₁₆FNO₂S