2,4(1H,3H)-Pyrimidinedione, 1-[(2R,3R,4S)-tetrahydro-3,4-dihydroxy-2-furanyl]- (9CI)

Base Information

Chemical Name:2,4(1H,3H)-Pyrimidinedione, 1-[(2R,3R,4S)-tetrahydro-3,4-dihydroxy-2-furanyl]- (9CI)
CAS No.:325683-85-0
Molecular Formula:C₈H₁₀N₂O₅
Molecular Weight:214.178
Hs Code.:
Mol file:325683-85-0.mol

Synonyms:2,4(1H,3H)-Pyrimidinedione, 1-[(2R,3R,4S)-tetrahydro-3,4-dihydroxy-2-furanyl]- (9CI)

Suppliers and Price of 2,4(1H,3H)-Pyrimidinedione, 1-[(2R,3R,4S)-tetrahydro-3,4-dihydroxy-2-furanyl]- (9CI)

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
1-((2R,3R,4S)-3,4-Dihydroxytetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione 97%
1g
$ 1062.00

Total 1 raw suppliers

Chemical Property of 2,4(1H,3H)-Pyrimidinedione, 1-[(2R,3R,4S)-tetrahydro-3,4-dihydroxy-2-furanyl]- (9CI)

Chemical Property:

PSA：104.55000
LogP:-2.21280

Purity/Quality:: 1-((2R,3R,4S)-3,4-Dihydroxytetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 2,4(1H,3H)-Pyrimidinedione, 1-[(2R,3R,4S)-tetrahydro-3,4-dihydroxy-2-furanyl]- (9CI)

There total 1 articles about 2,4(1H,3H)-Pyrimidinedione, 1-[(2R,3R,4S)-tetrahydro-3,4-dihydroxy-2-furanyl]- (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 325683-80-5
1-(2',3'-di-O-benzoyl-α-L-threofuranosyl)uracil

: 325683-85-0
1-(α-L-threofuranosyl)uracil

Guidance literature:: With triethylamine; In methanol; water; Heating;
DOI:10.1002/hlca.200290000

Reference yield: 22.0%

: 40615-36-9
4,4'-dimethoxytrityl chloride

: 325683-85-0
1-(α-L-threofuranosyl)uracil

: 1-{2'-O-[(4,4'-dimethoxytriphenyl)methyl]-α-L-threofuranosyl}uracil

: 325683-90-7
1-{3'-O-[(4,4'-dimethoxytriphenyl)methyl]-α-L-threofuranosyl}uracil

Guidance literature:: With 2,6-dimethylpyridine; silver trifluoromethanesulfonate; In dichloromethane; N,N-dimethyl-formamide; at 20 ℃;
DOI:10.1002/hlca.200290000

Reference yield:

: 325683-85-0
1-(α-L-threofuranosyl)uracil

: 1-{2'-O-[(2-cyanoethoxy)(diisopropylamino)phosphino]-3'-O-[(4,4'-dimethoxytriphenyl)methyl]-α-L-threofuranosyl}uracil

Guidance literature:: Multi-step reaction with 2 steps

1: 22 percent / 2,6-lutidine; Ag-Tf / dimethylformamide; CH₂Cl₂ / 20 °C

2: 74 percent / EtN(iPr)2 / CH₂Cl₂ / 18 h / 20 °C

With 2,6-dimethylpyridine; silver trifluoromethanesulfonate; N-ethyl-N,N-diisopropylamine; In dichloromethane; N,N-dimethyl-formamide;
DOI:10.1002/hlca.200290000