(S)-3,5-dichloro-4-(2-(3-(cyclopropylmethoxy)-4-(difluoromethoxy)phenyl)-2-((3-(methylsulfonamido)phenylthio)carbonyloxy)ethyl)pyridine 1-oxide?

Base Information

Chemical Name:(S)-3,5-dichloro-4-(2-(3-(cyclopropylmethoxy)-4-(difluoromethoxy)phenyl)-2-((3-(methylsulfonamido)phenylthio)carbonyloxy)ethyl)pyridine 1-oxide?
CAS No.:1428846-90-5
Molecular Formula:C₂₆H₂₄Cl₂F₂N₂O₇S₂
Molecular Weight:649.521
Hs Code.:

(S)-3,5-dichloro-4-(2-(3-(cyclopropylmethoxy)-4-(difluoromethoxy)phenyl)-2-((3-(methylsulfonamido)phenylthio)carbonyloxy)ethyl)pyridine 1-oxide?

Synonyms:(S)-3,5-dichloro-4-(2-(3-(cyclopropylmethoxy)-4-(difluoromethoxy)phenyl)-2-((3-(methylsulfonamido)phenylthio)carbonyloxy)ethyl)pyridine 1-oxide?

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (S)-3,5-dichloro-4-(2-(3-(cyclopropylmethoxy)-4-(difluoromethoxy)phenyl)-2-((3-(methylsulfonamido)phenylthio)carbonyloxy)ethyl)pyridine 1-oxide?

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Technology Process of (S)-3,5-dichloro-4-(2-(3-(cyclopropylmethoxy)-4-(difluoromethoxy)phenyl)-2-((3-(methylsulfonamido)phenylthio)carbonyloxy)ethyl)pyridine 1-oxide?

There total 4 articles about (S)-3,5-dichloro-4-(2-(3-(cyclopropylmethoxy)-4-(difluoromethoxy)phenyl)-2-((3-(methylsulfonamido)phenylthio)carbonyloxy)ethyl)pyridine 1-oxide? which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.4%

: 1428846-77-8
(S)-3,5-dichloro-4-(2-(3-(cyclopropylmethoxy)-4-(difluoromethoxy)phenyl)-2-((4-nitrophenoxy)carbonyloxy)-ethyl)pyridine 1-oxide

: 501950-20-5
N-(3-mercaptophenyl)methanesulfonamide

: 1428846-90-5
(S)-3,5-dichloro-4-(2-(3-(cyclopropylmethoxy)-4-(difluoromethoxy)phenyl)-2-((3-(methylsulfonamido)phenylthio)carbonyloxy)ethyl)pyridine 1-oxide?

Guidance literature:: With dmap; In dichloromethane; at 20 ℃; for 3h; Inert atmosphere;

Reference yield:

: 1428846-92-7
N,N′-(3,3′-disulfanediylbis(3,1-phenylene))dimethanesulfonamide

: 1428846-90-5
(S)-3,5-dichloro-4-(2-(3-(cyclopropylmethoxy)-4-(difluoromethoxy)phenyl)-2-((3-(methylsulfonamido)phenylthio)carbonyloxy)ethyl)pyridine 1-oxide?

Guidance literature:: Multi-step reaction with 2 steps

1: sodium tetrahydroborate; ethanol / 20 °C

2: dmap / dichloromethane / 3 h / 20 °C / Inert atmosphere

With dmap; sodium tetrahydroborate; ethanol; In dichloromethane;

Reference yield:

: (S)-3,5-dichloro-4-(2-(3-(cyclopropylmethoxy)-4-(difluoromethoxy)phenyl)-2-hydroxyethyl)pyridine 1-oxide

: 1428846-90-5
(S)-3,5-dichloro-4-(2-(3-(cyclopropylmethoxy)-4-(difluoromethoxy)phenyl)-2-((3-(methylsulfonamido)phenylthio)carbonyloxy)ethyl)pyridine 1-oxide?

Guidance literature:: Multi-step reaction with 2 steps

1: dmap / dichloromethane / 18 h / 20 °C

2: dmap / dichloromethane / 3 h / 20 °C / Inert atmosphere

With dmap; In dichloromethane;