(2S,3R,11bS)-2-((E)-2-Benzyloxy-vinyl)-9,10-dimethoxy-3-((Z)-propenyl)-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinoline

Base Information

• Chemical Name: (2S,3R,11bS)-2-((E)-2-Benzyloxy-vinyl)-9,10-dimethoxy-3-((Z)-propenyl)-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinoline
• CAS No.: 163814-74-2
• Molecular Formula: C₂₇H₃₃NO₃
• Molecular Weight: 419.564
• Mol file: 163814-74-2.mol

Synonyms:(2S,3R,11bS)-2-((E)-2-Benzyloxy-vinyl)-9,10-dimethoxy-3-((Z)-propenyl)-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinoline

Chemical Property of (2S,3R,11bS)-2-((E)-2-Benzyloxy-vinyl)-9,10-dimethoxy-3-((Z)-propenyl)-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinoline

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (2S,3R,11bS)-2-((E)-2-Benzyloxy-vinyl)-9,10-dimethoxy-3-((Z)-propenyl)-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinoline

There total 1 articles about (2S,3R,11bS)-2-((E)-2-Benzyloxy-vinyl)-9,10-dimethoxy-3-((Z)-propenyl)-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(S)-1-((Z)-4-Benzyloxy-but-2-enyl)-6,7-dimethoxy-2-((E)-penta-2,4-dienyl)-1,2,3,4-tetrahydro-isoquinoline → (2S,3R,11bS)-2-((E)-2-Benzyloxy-vinyl)-9,10-dimethoxy-3-((Z)-propenyl)-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinoline (163814-74-2)

Guidance literature:

With bisoxazoline-modified iron catalyst ; triethylaluminum; In toluene; at 50 ℃; for 6h;

DOI:10.1016/0040-4039(95)00443-G

Reference yield:

(2S,3R,11bS)-2-((E)-2-Benzyloxy-vinyl)-9,10-dimethoxy-3-((Z)-propenyl)-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinoline (163814-74-2) → (2R,3R,11bS)-2-(2-Benzyloxy-ethyl)-9,10-dimethoxy-3-propyl-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinoline

Guidance literature:

With hydrogen; Rh/Al₂O₃; In methanol; chloroform; at 25 ℃; for 20h; under 760 Torr;

DOI:10.1016/0040-4039(95)00443-G