2-Iododibenzothiophene

Base Information

• Chemical Name: 2-Iododibenzothiophene
• CAS No.: 177586-41-3
• Molecular Formula: C₁₂H₇IS
• Molecular Weight: 310.158
• Mol file: 177586-41-3.mol

Synonyms:2-iododibenzo[b,d]thiophene

Chemical Property of 2-Iododibenzothiophene

Chemical Property:

• Melting Point: 89.0 to 93.0 °C
• Boiling Point: 408.2±18.0 °C(Predicted)
• Density: 1.832±0.06 g/cm3(Predicted)

Purity/Quality:

97% ^*data from raw suppliers

2-Iododibenzothiophene ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Uses: 2-Iododibenzothiophene?is a thiophene derivative and is used in pharmaceutical synthesis.

Technology Process of 2-Iododibenzothiophene

There total 2 articles about 2-Iododibenzothiophene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

dibenzothiophene (132-65-0) → 2-iododibenzo[b,d]thiophene (177586-41-3)

Guidance literature:

With sulfuric acid; iodine; periodic acid; In water; acetic acid; at 60 ℃; for 4.5h;

Reference yield:

→ 2-iododibenzo[b,d]thiophene (177586-41-3)

Guidance literature:

nach Sandmeyer;

Reference yield: 93.0%

triphenylboroxine (3262-89-3) + 2-iododibenzo[b,d]thiophene (177586-41-3) → 2-phenyldibenzo[b,d]thiophene (3776-91-8)

Guidance literature:

triphenylboroxine; With potassium tert-butylate; zinc(II) chloride; In 1-methyl-pyrrolidin-2-one; at 23 ℃; for 1h; Inert atmosphere; Glovebox;

2-iododibenzo[b,d]thiophene; In 1-methyl-pyrrolidin-2-one; at 110 ℃; for 24h; Inert atmosphere; Glovebox;

DOI:10.1002/anie.201802813

upstream raw materials:

dibenzothiophene

Downstream raw materials:

N-(dibenzothiophene-2-yl)-N-phenyl-amine

2-phenyldibenzo[b,d]thiophene